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  • 1651.
    Yu, BZ
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology. MOLECULAR EVOLUTION.
    Poi, MJ
    Ramagopal, UA
    Jain, R
    Ramakumar, S
    Berg, OG
    Tsai, MD
    Sekar, K
    Jain, MK
    Structural basis of the anionic interface preference and kcat*-activation of pancreatic phospholipase A22000In: Biochemistry, Vol. 39, p. 12312-12323Article in journal (Refereed)
  • 1652.
    Yu, N
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Fu, YX
    Sambuughin, N
    Ramsay, M
    Jenkins, T
    Leskinen, E
    Patthy, L
    Jorde, LB
    Kuromori, T
    Li, WH
    Global patterns of human DNA sequence variation in a 10-kb region on chromosome 12001In: MOLECULAR BIOLOGY AND EVOLUTION, Vol. 18, no 2, p. 214-222Article in journal (Refereed)
  • 1653.
    Zamfir, M
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Effects of bryophytes and lichens on seedling emergence of alvar plants: evidence from greenhouse experiments2000In: OIKOS, ISSN 0030-1299, Vol. 88, no 3, p. 603-611Article in journal (Refereed)
    Abstract [en]

    Emergence of seedlings of four alvar grassland species (Arenaria serpyllifolia, Festuca ovina, Filipendula vulgaris and Veronica spicata) in bryophyte and lichen carpets was analysed in a series of greenhouse experiments. The aspects investigated were: th

  • 1654.
    Zamfir, M
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Goldberg, DE
    The effect of initial density on interactions between bryophytes at individual and community levels2000In: JOURNAL OF ECOLOGY, ISSN 0022-0477, Vol. 88, no 2, p. 243-255Article in journal (Refereed)
    Abstract [en]

    1 A glasshouse experiment was conducted with seven bryophyte species to determine the effects of competition. We tested whether competitive hierarchies varied with initial abundance (density and biomass) and between two different experimental approaches.

  • 1655. Zbinden, M
    et al.
    Mazzi, D
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology. Department of Ecology and Evolution, Animal Ecology. Zooekologi.
    Kunzler, R
    Largiader, C
    Bakker, TCM
    Corting virtual rivals ioncrease ejaculate size in sticklebacks (Gasterosteus aculeatus)2003In: Behavioral Ecology and Sociobiology, Vol. 54, p. 205-209Article in journal (Refereed)
  • 1656.
    Zenebe, Tadesse
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Ahlgren, Gunnel
    Boberg, M
    Fatty acid content of some freshwater fish of commercial importance from tropical lakes in the Ethiopian Rift Valley1998In: JOURNAL OF FISH BIOLOGY, ISSN 0022-1112, Vol. 53, no 5, p. 987-1005Article in journal (Refereed)
    Abstract [en]

    Fifty samples of freshwater fish, representing eight tropical species, were collected from Ethiopian Rift Valley lakes in order to study the variation of lipids and fatty acids (FA) both within and between species. Most specimens (36 samples) were low in

  • 1657.
    Zenebe, Tadesse
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Ahlgren, Gunnel
    Gustafsson, Inga-Britt
    Boberg, M
    Fatty acid and lipid content of Oreochromis niloticus L. in Ethiopian lakes - dietary effects of phytoplankton1998In: ECOLOGY OF FRESHWATER FISH, ISSN 0906-6691, Vol. 7, no 3, p. 146-158Article in journal (Refereed)
    Abstract [en]

    Herbivorous tilapia fish, Oreochromis niloticus L. (Cichlidae), collected from five Ethiopian lakes were analyzed for lipid and fatty acid contents of the dorsal muscle using spectrophotometry and gas-liquid chromatography. The results showed remarkable v

  • 1658.
    ZhaoZM,
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Jin, L
    Fu, YX
    Ramsay, M
    Jenkins, T
    Leskinen, E
    Pamilo, P
    Trexler, M
    Patthy, L
    Jorde, LB
    Ramos-Onsins, S
    Yu, N
    Li, WH
    Worlwide DNA sequence variation in a 10-kilobase noncoding region on human chromosome 222000In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 97, no 21, p. 11354-11358Article in journal (Refereed)
  • 1659.
    Zhou, Lihua
    et al.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology.
    Wu, Zhengyi
    Uppsala University, Music and Museums, The Linnean Gardens of Uppsala, Botanical Garden.
    Lidén, Magnus
    Oxelman, Bengt
    Silene2001In: Flora of China, Missouri Botanical Garden Press, St Louis, USA , 2001, Vol. 6, p. 66-100Chapter in book (Refereed)
  • 1660.
    Zhu, DQ, Chapuisat, M, Pamilo, P
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology. CONSERVATION BIOLOGY AND GENETICS.
    Highly variable social organization of colonies in the ant Formica cinerea.2003In: HereditasArticle in journal (Refereed)
  • 1661.
    Zimma, B
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Ecological Research Station, Ölands Skogsby.
    Ayasse, M
    Tengö, J
    Ibarra, F
    Schultz, C
    Francke, W
    Do social parasitic bumblebees use chemical weapons? (Hymenoptera, Apidae, Bombus norwegicus)2003In: J Comp Physiol A, Vol. 189, p. 769-775Article in journal (Refereed)
  • 1662.
    Zink, RM
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Blackwell-Rago, RC
    Ronquist, F
    The shifting roles of dispersal and vicariance in biogeography2000In: PROCEEDINGS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, ISSN 0962-8452, Vol. 267, no 1442, p. 497-503Article in journal (Refereed)
    Abstract [en]

    Dispersal and vicariance are often contrasted as competing processes primarily responsible for spatial and temporal patterns of biotic diversity. Recent methods of biogeographical reconstruction recognize the potential of both processes, and the emerging

  • 1663. Zwart, G.
    et al.
    van Hannen, E. J
    Kamst-van Agterveld, M. P.
    Van der Gucht, K.
    Lindström, E.S.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology. Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Ecology and Evolution, Limnology.
    van Wichelen, J.
    Lauridsen, T
    Crump, B. C.
    Han, S.-K.
    Declerck, S.
    Rapid Screening for Freshwater Bacterial Groups by Using Reverse Line Blot Hybridization2003In: Applied and Environmental Microbiology,, Vol. 69, p. 5875-5883Article in journal (Refereed)
  • 1664.
    Åberg, Karolina
    et al.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolution, Genomics and Systematics.
    Axelsson, Elin
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolution, Genomics and Systematics.
    Saetre, Peter
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology, Department of Animal Development and Genetics.
    Jiang, Lin
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology, Department of Animal Development and Genetics.
    Wetterberg, Lennart
    Pettersson, Ulf
    Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Genetics and Pathology.
    Lindholm, Eva
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology, Department of Animal Development and Genetics.
    Jazin, Elena
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology, Department of Animal Development and Genetics.
    Support for schizophrenia susceptibility locus on chromosome 2q detected in a Swedish isolate using a dense map of microsatellites and SNPs2008In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, ISSN 1552-485X, Vol. 147B, no 7, p. 1238-44Article in journal (Refereed)
    Abstract [en]

    Extended pedigrees are not only very useful to identify disease genes for rare Mendelian conditions, but they may also help unravel the genetics of complex diseases such as schizophrenia. In this study we performed genome-wide multipoint non-parametric linkage (NPL) score calculations using 825 microsatellites and 5,366 single nucleotide polymorphisms (SNPs), respectively, and searched for haplotypes shared by affected individuals, in three multiplex families including 29 genotyped affected individuals which in total contains 49 relative pairs useful for linkage studies. The most consistent results for microsatellites and SNPs were observed on 2q12.3-q14.1 (NPL scores 2.0, empirical P-value 0.009). However, the overall highest NPL score was observed on chromosome 2q33.3 using SNPs (NPL score 2.2, empirical P-value 0.007). Other chromosomal regions were detected on 5q15-q22.1, with microsatellites (NPL scores 1.7, empirical P-value 0.021) and with SNPs (NPL scores 2.0, empirical P-value 0.010) and on 5q23.1 (NPL score 1.9, empirical P-value 0.012) and 8q24.1-q24.2 (NPL score 2.1, empirical P-value 0.009) when using SNPs. The analysis of extended pedigrees allowed the search for haplotypes inherited identical by decent (IBD) by affected individuals. In all regions with NPL score >1.9 we found haplotypes inherited IBD by multiple cases. However, no common haplotypes were found for affected individuals in all families. In conclusion our NPL results support earlier findings suggesting that 2q and possibly 5q and 8q contain susceptibility loci for schizophrenia. Haplotype sharing in families helped to delimit the detected regions that potentially are susceptibility loci for schizophrenia.

  • 1665.
    Åberg, Karolina
    et al.
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolution, Genomics and Systematics, Evolutionary Biology.
    Saetre, Peter
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology, Department of Animal Development and Genetics.
    Jareborg, Niclas
    Jazin, Elena
    Uppsala University, Disciplinary Domain of Science and Technology, Biology, Department of Evolutionary Biology, Department of Animal Development and Genetics.
    Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia2006In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 103, no 19, p. 7482-7487Article in journal (Refereed)
    Abstract [en]

    The quaking viable mouse mutation (qkv) is a deletion including the 5′ regulatory region of the quaking gene (Qki), which causes body tremor and severe dysmyelination in mouse. The function of the human quaking gene, called quaking homolog KH domain RNA-binding (mouse) (QKI), is not well known. We have previously shown that QKI is a new candidate gene for schizophrenia. Here we show that human QKI mRNA levels can account for a high proportion (47%) of normal interindividual mRNA expression variation (and covariation) of six oligodendrocyte-related genes (PLP1, MAG, MBP, TF, SOX10, and CDKN1B) in 55 human brain autopsy samples from individuals without psychiatric diagnoses. In addition, the tightly coexpressed myelin-related genes (PLP1, MAG, and TF) have decreased mRNA levels in 55 schizophrenic patients, as compared with 55 control individuals, and most of this difference (68–96%) can be explained by variation in the relative mRNA levels of QKI-7kb, the same QKI splice variant previously shown to be down-regulated in patients with schizophrenia. Taken together, our results suggest that QKI levels may regulate oligodendrocyte differentiation and maturation in human brain, in a similar way as in mouse. Moreover, we hypothesize that previously observed decreased activity of myelin-related genes in schizophrenia might be caused by disturbed QKI splicing.

  • 1666.
    Ågren, L
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Hallberg, E
    Flagellar sensilla of bumble bee males (Hymenoptera, Apidae, Bombus)1996In: APIDOLOGIE, ISSN 0044-8435, Vol. 27, no 6, p. 433-444Article in journal (Refereed)
    Abstract [en]

    The flagellar sensillar distribution in males of 12 species of bumble bees, including five species with large-eyed males, did not show any conspicuous species-specific or behavior-related pattern. The sensillar types were morphologically similar to those

  • 1667.
    Ågren, Lennart
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Hallberg, Eric
    Flagellar sensilla of bumble bee males (Hymenoptera, Apidae, Bombus).1996In: Apidologie, Vol. 27, p. 433-444Article in journal (Refereed)
  • 1668.
    Ödeen, Anders
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Effects of Post-Glacial Range Expansions and Population Bottlenecks on Species Richness2001Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    This thesis relates modern speciation theory to the effects of sudden changes in the range and size of populations. Special reference is made to the climatic oscillations during the Quaternary ice ages. A meta-analysis of laboratory experiments showed that support for allopatric speciation is weak, especially for the peripatric type of allopatric speciation. Furthermore, factors traditionally believed to increase the likelihood of speciation have had little effect on the generation of reproductive isolation in speciation experiments. However, the method of testing reproductive isolation appeared important, in the sense that experimentally derived sister populations were likely to demonstrate reproductive isolation from each other but not from the unaffected mother population. Raw data from mating tests showed that the poor isolation between mother and daughter populations was an effect of asymmetric mate preferences towards males from the mother population. This suggests that peripatric speciation can be effective in generating reproductive isolation between sister populations. The proposed mechanism is that males become less attractive to females by losing certain secondary sexual traits during population bottlenecks, and that females shift their preferences towards other male traits. Support for this mode of speciation is found in the widespread bird genus Motacilla (wagtails). This genus is characterised by extensive plumage variation and contains a large number of widely distributed taxa in the northern parts of its distribution. This thesis shows that taxonomic diversity of wagtails is inversely related to complexity in song and to diversity in molecular and mitochondrial markers. The northern taxa seem to be descendants of southern populations, which were subjected to bottlenecks during expansions into re-opened habitats after the last ice age. The bottlenecks would not only reduce genetic diversity but also inhibit cultural transmission of song to the leading edge of colonisers, allowing sexual selection on other traits, such as plumage. Rapid plumage differentiation among wagtail taxa appears to be a recurrent process and has lead to convergent evolution, making the currently recognised species Motacilla flava (Yellow Wagtail) polyphyletic.

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  • 1669.
    Ödeen, Anders
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology. Department of Ecology and Evolution, Animal Ecology. Zooekologi.
    Björklund, Mats
    Department of Ecology and Evolution, Animal Ecology.
    Dynamics in the evolution of sexual traits: losses and gains, radiation and convergence in yellow wagtails (Motacilla flava)2003In: Molecular Ecology, ISSN 09621083, Vol. 12, no 8, p. 2113-2130Article in journal (Refereed)
    Abstract [en]

    We analyse patterns of genetic diversity and song complexity in the Palaearctic yellow wagtail (Motacilla flava), a highly polytypic species complex. Mitochondrial and nuclear DNA show that the complex is polyphyletic, despite parallel plumage variation i

  • 1670. Ödeen, Anders
    et al.
    Håstad, Olle
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology, Animal Ecology.
    Complex Distribution of Avian Color Vision Systems Revealed by Sequencing the SWS1 Opsin from Total DNA2003In: Molecular Biology and Evolution, ISSN 0737-4038, Vol. 20, no 6, p. 855–861-Article in journal (Refereed)
  • 1671.
    Ödeen, Anders
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Håstad, Olle
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Complex distribution of avian color vision systems revealed by sequencing the SWS1 opsin from total DNA2003In: Molecular Biology and Evolution, ISSN 0737-4038, Vol. 20, no 6, p. 855-861Article in journal (Refereed)
    Abstract [en]

    To gain insights into the evolution and ecology of visually acute animals such as birds, biologists often need to understand how these animals perceive colors. This poses a problem, since the human eye is of a different design than that of most other anim

  • 1672.
    Östlund-Nilsson, Sara
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Female choice and paternal care in the fifteen-spined stickleback, Spinachia spinachia2000Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    In the fifteen-spined stickleback, Spinachia spinachia, males provide females with direct benefits by fanning, cleaning and guarding the offspring. Males announce their parental skills through intense body shakes during courtship. Females preferred to mate with more intensely shaking males. As a result, females got better fathers for their offspring, as such males achieved a higher hatching success. Not only did male behavioural cues attract females, but males also used their nests as extrabodily ornaments. The nest is held together with shiny secretional threads consisting of a glycoprotein. Females chose to spawn in nests with more secretional threads. A likely reason for this is that the threads are metabolically costly for the male to produce and the amount of secretion indicates a male's nutritional status, which is of great importance as parental duties are energetically costly. Moreover, females preferred nests built high up in the vegetation, as such nests were safer from egg predators. Competition with other males for females favoured males building higher nests than did their neighbours, probably because females preferred high nests. Male-male interactions, such as sneaking and egg stealing, caused decreased paternity among males in nature as assessed by a microsatellite analysis. Males adjusted their paternal effort according to their previous investment in the brood, but not according to paternity. Thus, female choice is based on multiple cues and results in better paternal care. Males invest in courtship, male-male competition, nest construction and paternal care, the outcome determining their success in mate attraction.

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  • 1673.
    Øverli, Ø., Kotzian, S. and Winberg, S.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Effects of cortisol on aggression and locomotor activity in rainbow trout.2002In: Hormones and Behavior, Vol. 42, p. 53-61Article in journal (Refereed)
  • 1674.
    Øverli, Ø.
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology. Department of Physiology and Developmental Biology, Comparative Physiology.
    Pottinger, TG
    Carrick, TR
    Overli, E
    Winberg, S
    Department of Physiology and Developmental Biology, Comparative Physiology. jämförande fysiologi.
    Brain monoaminergic activity in rainbow trout selected for high and low stress responsiveness.2001In: Brain Behavior and Evolution, Vol. 57, p. 214-224Article in journal (Refereed)
  • 1675.
    Øverli, Ø
    et al.
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology. Department of Physiology and Developmental Biology, Comparative Physiology.
    Pottinger, TG
    Carrick, TR
    Overli, E
    Winberg, S
    Department of Physiology and Developmental Biology, Comparative Physiology. jämförande fysiologi.
    Differences in behaviour between rainbow trout selected for high and low2001In: Journal of Experimental Biology, Vol. 205, p. 391-395Article in journal (Refereed)
  • 1676.
    Øverli, Øyvind
    Uppsala University, Teknisk-naturvetenskapliga vetenskapsområdet, Faculty of Science and Technology, Biology, Department of Evolutionary Biology.
    Behavioural and Neuroendocrine Effects of Stress in Salmonid Fish2001Doctoral thesis, comprehensive summary (Other academic)
    Abstract [en]

    Stress can affect several behavioural patterns, such as food intake and the general activity level of an animal. The central monoamine neurotransmitters serotonin, dopamine, and norepinephrine are important in the mediation of both behavioural and neuroendocrine stress effects. This thesis describes studies of two salmonid fish model systems: Fish that become socially dominant or subordinate when reared in pairs, and rainbow trout (Oncorhynchus mykiss) genetically selected for high (HR) and low (LR) stress responsiveness, in terms of stress induced cortisol release. Socially subordinate individuals are often subject to chronic stress, and it was found that plasma cortisol and brain monoaminergic activity rapidly increased in subordinate fish during the initial 24 h period following fights for social dominance in pairs of rainbow trout. In pairs of Arctic char (Salvelinus alpinus), subordinate individuals were characterised by an inhibition of food intake and aggression, and low spontaneous locomotion. Appetite inhibition in subordinate fish was reversed by subsequent rearing in isolation, and this effect was probably related to a concomitant decrease in brain serotonergic activity. Furthermore, differential stress responsiveness in HR and LR rainbow trout was associated with differences in behaviour, as well as changes in brain monoaminergic activity. HR fish displayed higher locomotor activity when challenged by a conspecific intruder. This response was probably related to a larger stress induced activation of brain dopaminergic systems in these fish. Finally it was shown that the steroid 'stress-hormone' cortisol has dose- and context-dependent behavioural effects in fish, as has been described in mammals. Specifically, short- term cortisol treatment elevated the behavioural response to a territorial intruder, while long-term treatment, like chronic stress, had the opposite effect, inhibiting locomotor activity and aggression. It is concluded that the signalling systems involved in behavioural and neuroendocrine control during stress display extensive similarities between teleost fishes and mammals.

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31323334 1651 - 1676 of 1676
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