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  • 301.
    Brusini, Irene
    et al.
    KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Huddinge, Sweden.
    Carneiro, Miguel
    Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, Vairao, Portugal; Univ Porto, Dept Biol, Fac Ciencias, Porto, Portugal.
    Wang, Chunliang
    KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Huddinge, Sweden.
    Rubin, Carl-Johan
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Ring, Henrik
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Medicinsk utvecklingsbiologi.
    Afonso, Sandra
    Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, Vairao, Portugal.
    Blanco-Aguiar, José A.
    Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, Vairao, Portugal; CSIC, Inst Invest Recursos Cineget IREC, Ciudad Real, Spain; UCLM, CSIC, Ciudad Real, Spain.
    Ferrand, Nuno
    Univ Porto, Ctr Invest Biodiversidade & Recursos Genet CIBIO, InBIO, Vairao, Portugal; Univ Porto, Dept Biol, Fac Ciencias, Porto, Portugal; Univ Johannesburg, Dept Zool, Johannesburg, South Africa.
    Rafati, Nima
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab.
    Villafuerte, Rafael
    CSIC, IESA, Cordoba, Spain.
    Smedby, Örjan
    KTH Royal Inst Technol, Dept Biomed Engn & Hlth Syst, Huddinge, Sweden.
    Damberg, Peter
    Karolinska Univ Hosp, Karolinska Expt Res & Imaging Ctr, Solna, Sweden.
    Hallböök, Finn
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Medicinsk utvecklingsbiologi.
    Fredriksson, M
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi. Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
    Andersson, Leif
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för medicinsk biokemi och mikrobiologi. Uppsala universitet, Science for Life Laboratory, SciLifeLab. Texas A&M Univ, Coll Vet Med & Biomed Sci, Dept Vet Integrat Biosci, College Stn, TX USA; Swedish Univ Agr Sci, Dept Anim Breeding & Genet, Uppsala, Sweden.
    Changes in brain architecture are consistent with altered fear processing in domestic rabbits2018Inngår i: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, E-ISSN 1091-6490, Vol. 115, nr 28, s. 7380-7385Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The most characteristic feature of domestic animals is their change in behavior associated with selection for tameness. Here we show, using high-resolution brain magnetic resonance imaging in wild and domestic rabbits, that domestication reduced amygdala volume and enlarged medial prefrontal cortex volume, supporting that areas driving fear have lost volume while areas modulating negative affect have gained volume during domestication. In contrast to the localized gray matter alterations, white matter anisotropy was reduced in the corona radiata, corpus callosum, and the subcortical white matter. This suggests a compromised white matter structural integrity in projection and association fibers affecting both afferent and efferent neural flow, consistent with reduced neural processing. We propose that compared with their wild ancestors, domestic rabbits are less fearful and have an attenuated flight response because of these changes in brain architecture.

  • 302.
    Bränn, Emma
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Obstetrisk och reproduktiv hälsoforskning.
    Fransson, Emma
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Obstetrisk och reproduktiv hälsoforskning. Karolinska Institutet, Stockholm, Sweden..
    White, Richard A
    Norwegian Institute of Public Health, Oslo, Norway.
    Papadopoulos, Fotios C
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
    Edvinsson, Åsa
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Reproduktiv hälsa.
    Kamali-Moghaddam, Masood
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för immunologi, genetik och patologi.
    Cunningham, Janet L
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
    Sundström Poromaa, Inger
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Reproduktiv hälsa.
    Skalkidou, Alkistis
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Obstetrisk och reproduktiv hälsoforskning.
    Inflammatory markers in women with postpartum depressive symptoms2018Inngår i: Journal of Neuroscience Research, ISSN 0360-4012, E-ISSN 1097-4547Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Postpartum depression (PPD) is a devastating disorder affecting not only more than 10% of all women giving birth, but also the baby, the family, and the society. Compiling evidence suggests the involvement of the immune system in the pathophysiology of major depression; yet, the immune response in perinatal depression is not as well studied. The aim of this study was to investigate the alterations in peripheral levels of inflammatory biomarkers in 169 Swedish women with and without depressive symptoms according to the Edinburgh postnatal depression scale or the M.I.N.I neuropsychiatric interview at eight weeks postpartum. Among the 70 markers analyzed with multiplex proximity extension assay, five were significantly elevated in women with postpartum depressive symptoms in the adjusted LASSO logistic regression analysis: Tumor necrosis factor ligand superfamily member (TRANCE) (OR-per 1 SD increase = 1.20), Hepatocyte growth factor (HGF) (OR = 1.17) Interleukin (IL)-18 (OR = 1.06), Fibroblast growth factor 23 (FGF-23) (OR = 1.25), and C-X-C motif chemokine 1 (CXCL1) (OR 1.11). These results indicate that women with PPD have elevated levels of some inflammatory biomarkers. It is, therefore, plausible that PPD is associated with a compromised adaptability of the immune system.

  • 303.
    Buhrman, Monica
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Guided Internet-Based Cognitive Behaviour Therapy for Chronic Pain2012Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    Chronic pain is a one of the most common causes of disability and sick leave. Psychological factors play a central role in the experience of pain and are important in the management of pain. However, for many people with chronic pain CBT is not available. There is a need to develop alternative ways to deliver treatments that reach more individuals with chronic pain. Internet-based treatments have been shown to be effective for several disorders and recent research suggests that internet-based CBT for chronic pain can be effective. The present thesis included four randomized controlled studies with the aim of evaluating whether guided internet-based treatments based on CBT can help individuals with chronic pain regarding psychological variables.

    Study I investigated the effects of an internet-based CBT intervention with telephone support for chronic back pain. The study showed reductions in some variables assessed.     

    Study II investigated the effects of an internet-based CBT intervention for chronic back pain without telephone support and with a live structured interview before inclusion. It was found that the treatment can reduce some of the distress associated with chronic pain.

    Study III investigated the effects of a guided internet-delivered CBT as a secondary intervention. Participants were patients who had previously completed multidisciplinary treatment at a pain management unit. Results showed that the internet-based treatment can be a feasible option for persons with residual problems after completed pain rehabilitation. Effects remained at six-month follow-up.   

    Study IV focused on the effect of a guided internet-delivered acceptance and commitment therapy (ACT) for persons with chronic pain. Results suggest that an internet-delivered ACT treatment can help persons with chronic pain. Effects remained at six-month follow-up.

    In conclusion, guided internet-based CBT can decrease distress associated with chronic pain.

    Delarbeid
    1. Controlled trial of Internet-based treatment with telephone support for chronic back pain
    Åpne denne publikasjonen i ny fane eller vindu >>Controlled trial of Internet-based treatment with telephone support for chronic back pain
    2004 (engelsk)Inngår i: Pain, ISSN 0304-3959, E-ISSN 1872-6623, Vol. 111, nr 3, s. 368-377Artikkel i tidsskrift (Fagfellevurdert) Published
    HSV kategori
    Forskningsprogram
    Psykologi
    Identifikatorer
    urn:nbn:se:uu:diva-183336 (URN)10.1016/j.pain.2004.07.021 (DOI)15363881 (PubMedID)
    Tilgjengelig fra: 2012-10-24 Laget: 2012-10-24 Sist oppdatert: 2017-12-07bibliografisk kontrollert
    2. Guided internet-based cognitive behavioural treatment for chronic back pain reduces pain catastrophizing: a randomized controlled trial
    Åpne denne publikasjonen i ny fane eller vindu >>Guided internet-based cognitive behavioural treatment for chronic back pain reduces pain catastrophizing: a randomized controlled trial
    Vise andre…
    2011 (engelsk)Inngår i: Journal of Rehabilitation Medicine, ISSN 1650-1977, E-ISSN 1651-2081, Vol. 43, nr 6, s. 500-505Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    Objective: The aim of this study was to investigate whether an Internet-based cognitive behavioural intervention would have an effect on the symptoms of chronic back pain. Design: Experimental design with a treatment group and a control group measured before and after a treatment period. Subjects: Participants who met the criteria for chronic back pain (n = 54). Methods: All participants were screened in a live, structured interview before inclusion. The study period was 12 weeks and the treatment consisted of education, cognitive skills acquisition, behavioural rehearsal, generalization and maintenance. The main outcome of interest was the catastrophizing subscale of the Coping Strategies Questionnaire. Results: There were statistically significant reductions from pre- to post-treatment in catastrophizing in the treatment group, and an improvement in quality of life for the treatment group. However, most outcome measures did not indicate a positive treatment outcome. On a scale measuring pain catastrophizing, 58% (15/26) of the treated participants showed reliable improvement, compared with 18% (5/28) of the control group. Conclusion: Internet-based cognitive behavioural therapy can serve as a complement for individuals with chronic pain who prefer this treatment and have difficulties accessing specialist treatment facilities.

    Emneord
    chronic back pain, Internet-based treatment, pain management programme, minimal therapist contact, cognitive behavioural therapy
    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-155234 (URN)10.2340/16501977-0805 (DOI)000291242400007 ()
    Tilgjengelig fra: 2011-06-21 Laget: 2011-06-20 Sist oppdatert: 2017-12-11bibliografisk kontrollert
    3. Guided Internet-delivered cognitive behavioural therapy for chronic pain patients who have residual symptoms after rehabilitation: Randomized controlled trial
    Åpne denne publikasjonen i ny fane eller vindu >>Guided Internet-delivered cognitive behavioural therapy for chronic pain patients who have residual symptoms after rehabilitation: Randomized controlled trial
    Vise andre…
    2013 (engelsk)Inngår i: European Journal of Pain, ISSN 1090-3801, E-ISSN 1532-2149, Vol. 17, nr 5, s. 753-765Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    Background Chronic pain can be treated with cognitive behavioural therapy delivered in multidisciplinary settings. However, relapse is likely, and there is a need for cost-effective secondary interventions for persons with residual problems after rehabilitation. The aim of the present study was to investigate the effects of a guided Internet-delivered cognitive behavioural intervention for patients who had completed multidisciplinary treatment at a pain management unit. Methods A total of 72 persons with residual pain problems were included in the study and were randomized to either treatment for 8 weeks or to a control group who were invited to participate in a moderated online discussion forum. The participants had different chronic pain conditions, and a majority were women (72%). Twenty-two percent of the participants dropped out of the study before the post-treatment assessment. Results Intent-to-treat analyses demonstrated differences on the catastrophizing subscale of the Coping Strategies Questionnaire (Cohen's d=0.70), in favour of the treatment group but a small within-group effect. Differences were also found on other measures of pain-related distress, anxiety and depressive symptoms. A 6-month follow-up exhibited maintenance of improvements. Conclusions We conclude that Internet-delivered treatment can be partly effective for persons with residual problems after completed pain rehabilitation.

    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-183338 (URN)10.1002/j.1532-2149.2012.00244.x (DOI)000316810000013 ()23139021 (PubMedID)
    Tilgjengelig fra: 2012-10-24 Laget: 2012-10-24 Sist oppdatert: 2017-12-07bibliografisk kontrollert
    4. Guided Internet-delivered acceptance and commitment therapy for chronic pain patients: a randomized controlled trial
    Åpne denne publikasjonen i ny fane eller vindu >>Guided Internet-delivered acceptance and commitment therapy for chronic pain patients: a randomized controlled trial
    Vise andre…
    2013 (engelsk)Inngår i: Behaviour Research and Therapy, ISSN 0005-7967, E-ISSN 1873-622X, Vol. 51, nr 6, s. 307-315Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    Acceptance and commitment therapy (ACT) interventions for persons with chronic pain have recently received empirical support. ACT focuses on reducing the disabling influences of pain through targeting ineffective control strategies and teaches people to stay in contact with unpleasant emotions, sensations, and thoughts. The aim of the present study was to investigate the effect of a guided internet-delivered ACT intervention for persons with chronic pain. A total of 76 patients with chronic pain were included in the study and randomized to either treatment for 7 weeks or to a control group that participated in a moderated online discussion forum. Intent-to-treat analyses showed significant increases regarding activity engagement and pain willingness. Measurements were provided with the primary outcome variable Chronic Pain Acceptance Questionnaire which was in favour of the treatment group. Reductions were found on other measures of pain-related distress, anxiety and depressive symptoms. A six month follow-up showed maintenance of improvements. We conclude that an acceptance based internet-delivered treatment can be effective for persons with chronic pain.

    Emneord
    Internet-delivered CBT, Chronic pain, Acceptance and commitment therapy, Mindfulness, Guided self-help
    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-183341 (URN)10.1016/j.brat.2013.02.010 (DOI)000319175400010 ()23548250 (PubMedID)
    Tilgjengelig fra: 2012-10-24 Laget: 2012-10-24 Sist oppdatert: 2017-12-07
  • 304.
    Buhrman, Monica
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    ICBT for chronic pain2012Inngår i: ICB for chronic pain, 2012Konferansepaper (Fagfellevurdert)
  • 305.
    Buhrman, Monica
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Internet-delivered psychologic treatment for chronic pain2015Konferansepaper (Fagfellevurdert)
  • 306.
    Buhrman, Monica
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Fredriksson, Anders
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Edström, G.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Shafiei, D.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Tärnqvist, C.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Ljóttson, B.
    Hursti, Timo
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Gordh, Torsten
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Anestesiologi och intensivvård.
    Andersson, G.
    Guided Internet-delivered cognitive behavioural therapy for chronic pain patients who have residual symptoms after rehabilitation: Randomized controlled trial2013Inngår i: European Journal of Pain, ISSN 1090-3801, E-ISSN 1532-2149, Vol. 17, nr 5, s. 753-765Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background Chronic pain can be treated with cognitive behavioural therapy delivered in multidisciplinary settings. However, relapse is likely, and there is a need for cost-effective secondary interventions for persons with residual problems after rehabilitation. The aim of the present study was to investigate the effects of a guided Internet-delivered cognitive behavioural intervention for patients who had completed multidisciplinary treatment at a pain management unit. Methods A total of 72 persons with residual pain problems were included in the study and were randomized to either treatment for 8 weeks or to a control group who were invited to participate in a moderated online discussion forum. The participants had different chronic pain conditions, and a majority were women (72%). Twenty-two percent of the participants dropped out of the study before the post-treatment assessment. Results Intent-to-treat analyses demonstrated differences on the catastrophizing subscale of the Coping Strategies Questionnaire (Cohen's d=0.70), in favour of the treatment group but a small within-group effect. Differences were also found on other measures of pain-related distress, anxiety and depressive symptoms. A 6-month follow-up exhibited maintenance of improvements. Conclusions We conclude that Internet-delivered treatment can be partly effective for persons with residual problems after completed pain rehabilitation.

  • 307.
    Buhrman, Monica
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Fältenhag, Sofia
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Ström, Lars
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Andersson, Gerhard
    Controlled trial of Internet-based treatment with telephone support for chronic back pain2004Inngår i: Pain, ISSN 0304-3959, E-ISSN 1872-6623, Vol. 111, nr 3, s. 368-377Artikkel i tidsskrift (Fagfellevurdert)
  • 308.
    Buhrman, Monica
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Gordh, Torsten
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper.
    Andersson, Gerhard
    Internet interventions for chronic pain including headache: A systematic review2016Inngår i: Internet Interventions, ISSN 2214-7829, Vol. 4, s. 17-34Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Chronic pain is a major health problem and behavioral based treatments have been shown to be effective. However, the availability of these kinds of treatments is scarce and internet-based treatments have been shown to be promising in this area. The objective of the present systematic review is to evaluate internet-based interventions for persons with chronic pain. The specific aims are to do an updated review with a broad inclusion of different chronic pain diagnoses and to assess disability and pain and also measures of catastrophizing, depression and anxiety. A systematic search identified 891 studies and 22 trials were selected as eligible for review. Two of the selected trials included children/youth and five included individuals with chronic headache and/or migraine. The most frequently measured domain reflected in the primary outcomes was interference/disability, followed by catastrophizing. Result across the studies showed a number of beneficial effects. Twelve trials reported significant effects on disability/interference outcomes and pain intensity. Positive effects were also found on psychological variable such as catastrophizing, depression and anxiety. Several studies (n = 12) were assessed to have an unclear level of risk bias. The attrition levels ranged from 4% to 54% where the headache trials had the highest drop-out levels. However, findings suggest that internet-based treatments based on cognitive behavioural therapy (CBT) are efficacious measured with different outcome variables. Results are in line with trials in clinical settings. Meta-analytic statistics were calculated for interference/disability, pain intensity, catastrophizing and mood ratings. Results showed that the effect size for interference/disability was Hedge's g = − 0.39, for pain intensity Hedge's g = − 0.33, for catastrophizing Hedge's g = − 0.49 and for mood variables (depression) Hedge's g = − 0.26.

  • 309.
    Buhrman, Monica
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Skoglund, Astrid
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Husell, Josefin
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Bergström, Kristina
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Gordh, Torsten
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper, Anestesiologi och intensivvård.
    Hursti, Timo
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Bendelin, Nina
    Furmark, Tomas
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Andersson, Gerhard
    Guided Internet-delivered acceptance and commitment therapy for chronic pain patients: a randomized controlled trial2013Inngår i: Behaviour Research and Therapy, ISSN 0005-7967, E-ISSN 1873-622X, Vol. 51, nr 6, s. 307-315Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Acceptance and commitment therapy (ACT) interventions for persons with chronic pain have recently received empirical support. ACT focuses on reducing the disabling influences of pain through targeting ineffective control strategies and teaches people to stay in contact with unpleasant emotions, sensations, and thoughts. The aim of the present study was to investigate the effect of a guided internet-delivered ACT intervention for persons with chronic pain. A total of 76 patients with chronic pain were included in the study and randomized to either treatment for 7 weeks or to a control group that participated in a moderated online discussion forum. Intent-to-treat analyses showed significant increases regarding activity engagement and pain willingness. Measurements were provided with the primary outcome variable Chronic Pain Acceptance Questionnaire which was in favour of the treatment group. Reductions were found on other measures of pain-related distress, anxiety and depressive symptoms. A six month follow-up showed maintenance of improvements. We conclude that an acceptance based internet-delivered treatment can be effective for persons with chronic pain.

  • 310.
    Buhrman, Monica
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Syk, Martin
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Burvall, Olle
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Hartig, Terry
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Gordh, Torsten
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kirurgiska vetenskaper.
    Andersson, Gerhard
    Individualized Guided Internet-delivered Cognitive Behaviour Therapy for Chronic Pain Patients with Comorbid Depression and Anxiety: A Randomized Controlled Trial2015Inngår i: The Clinical Journal of Pain, ISSN 0749-8047, E-ISSN 1536-5409, Vol. 31, nr 6, s. 504-516Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Depression and anxiety are commonly seen in patients with chronic pain which affects the patient´s daily life functioning. Although considerable attention has been devoted to explain why depression and anxiety are frequent comorbid with chronic pain, little empirical work has been conducted on interventions that target depression and anxiety and chronic pain. The present study was designed to test an individualized cognitive-behavioral treatment delivered through the internet for persons with chronic pain and emotional distress. A total of 52 patients with chronic pain and depression were included and randomized to either treatment for 8 weeks or to a control group that participated in a moderated online discussion forum. Intent-to-treat analyses showed significant decreases regarding depressive symptoms and pain disability in the treatment group. Results on the primary outcomes of depression and anxiety were in favour of the treatment group. Reductions were also found on pain catastrophizing. One year follow-up showed maintenance of improvements. We conclude that an individualized guided internet-delivered treatment based on cognitive behaviour therapy can be effective for persons with chronic pain comorbid emotional distress.

  • 311.
    Bujacz, Aleksandra
    et al.
    Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
    Eib, Constanze
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Toivanen, Susanna
    Academy of Health, Care and Social Welfare, Mälardalen University, Västerås, Sweden ; Department of Public Health Sciences, Stockholm University, Stockholm, Sweden.
    Not All Are Equal: A Latent Profile Analysis of Well-Being among the Self-Employed2019Inngår i: Journal of Happiness Studies, ISSN 1389-4978, E-ISSN 1573-7780Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This study uses a person-centered approach to distinguish between subpopulations of self-employed individuals using multidimensional well-being indicators. Data were obtained from European Social Survey including a sample of 3461 self-employed individuals from 29 European countries. The analysis has empirically identified six distinct profiles named ‘unhappy’, ‘languishing’, ‘happy’, ‘satisfied’, ‘passionate’, and ‘flourishing’. The profiles were associated with significant differences in well-being, health and work-related variables. The results highlight the heterogeneity of the self-employed population, and describe the complex—both hedonic and eudaimonic—character of the well-being concept in this population.

  • 312.
    Burell, Gunilla
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap.
    Behavior As The Key Component In Psychological Interventions For CHD Patients2016Inngår i: International Journal of Behavioral Medicine, ISSN 1070-5503, E-ISSN 1532-7558, Vol. 23, s. S208-S208Artikkel i tidsskrift (Fagfellevurdert)
  • 313.
    Burell, Gunilla
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Allmänmedicin och preventivmedicin.
    Norlund, Fredrika
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Psykosocial onkologi och stödjande vård.
    Olsson, Erik
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Psykosocial onkologi och stödjande vård.
    Pavulans, Paul
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Psykosocial onkologi och stödjande vård.
    Kurt, Svärdsudd
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Allmänmedicin och preventivmedicin.
    Affective Outcomes in the SUPRIM Stress Management Program for Post-Myocardial Infarction Patients2014Konferansepaper (Fagfellevurdert)
    Abstract [en]

    Background

    The Interheart Study showed that psychosocial stress increased the risk of myocardial infarction (OR 2.67). The Secondary Prevention in Uppsala Primary healthcare project (SUPRIM) tested whether stress management after myocardial infarction could decrease risk of recurrent cardiovascular events. SUPRIM was a randomized controlled trial in which CHD patients attended a CBT group stress management program. During 94 months of follow-up there was a 45% reduction of recurrent myocardial infarctions (MI) in the intervention group. There were no differences between intervention and control patientes in standard risk factors. Thus, we assumed that psychological mechanisms could explain the effects on hard endpoints.

    Method

    362 MI patients were assessed by a package of self-rating psychometric instrument, and this paper examined whether hostility, time urgency, depression, somatic anxiety, and vital exhaustion decreased more in the intervention group than in the control group. Data collected from 5 points of measurement over 24 months were analyzed with multi-linear regression.

    Results

    The intervention had a significant effect on hostility, time urgency, and somatic anxiety. Vital exhaustion and depression scores showed no differences. There was a significant relationship between attendance rate and decrease of hostility, but no association between attendance rate and levels of vital exhaustion or depression.

    Conclusions

    Treatment effects were demonstrated in measures that assessed emotional reactivity. These changes are possibly linked to physiological and hormonal mechanisms. However, it is to a considerable degree still unknown why and how the stress management intervention impacts disease endpoints.

  • 314. Busch, C
    et al.
    Staar, H
    Åborg, Carl
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Roscher, S
    Ducki, A
    The neglected employees: Work-life balance and a stress intervention program for low-qualified workers2010Inngår i: Contemporary occupational health psychology: Global perpespectives on research, education and practice (vol.1) / [ed] Houdmont, J. & Leka, S., Chichester, UK: Wiley-Blackwell, 2010Kapittel i bok, del av antologi (Fagfellevurdert)
  • 315.
    Bäckelie, Anna
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Leadership Style and Readiness Requirement in Job Advertisements: Exploring gender differences in wording appeal within technological corporate culture2018Independent thesis Advanced level (degree of Master (Two Years)), 20 poäng / 30 hpOppgave
    Abstract [en]

    Organizational leadership is predominantly male, even after decades of effort to even out this gap. The gender gap in corporal leadership was here assessed by investigating the possible effect of job advertisement configuration. Requesting a democratic or autocratic leadership style and high or low level of readiness for the leadership position in job advertisements was hypothesized to affect their appreciated appeal differently depending on the reader’s gender. A democratic leadership style and a low level of readiness requirement was thought to appeal more to women. Additionally, an effect of nearness to a manager of the same sex on the appreciated likelihood of applying for a leadership position was investigated, in line with the theory of same-sex role models. Seventy-nine male and seventy-seven female employees from a technical department within a global industrial company were included in the study where they rated manipulated company job advertisements’ appeal and filled out a survey. The results revealed no gender difference in the employees’ appeal ratings depending on the two variables. No difference in likelihood of applying for a leadership position was found, regardless of same-sex managerial nearness. The unique characteristics of the sample used induces a discussion of when advertisement wording matters and matters not.

  • 316. Böhm, Tomas
    et al.
    Kaplan, Suzanne
    Hämnd eller upprättelse: hämndspiralens psykologi2009 (oppl. 2)Bok (Annet (populærvitenskap, debatt, mm))
  • 317.
    Börjeson S, Hursti TJ, Tishelman C, Peterson C, Steineck G
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Treatment of nausea and emesis during cancer chemptherapy: Discrepancies between antiemetic effect and well-being2002Inngår i: Journal of pain and symptom management, Vol. 24, nr 3, s. 345-358Artikkel i tidsskrift (Fagfellevurdert)
  • 318.
    Börjesson, Erik
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Poom, Leo
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Visual slant-contrast across space and attributes2002Inngår i: Journal of Vision, ISSN 1534-7362, E-ISSN 1534-7362, Vol. 2, nr 7, s. 91a-Artikkel i tidsskrift (Annet vitenskapelig)
  • 319.
    Cajander, Åsa
    et al.
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Människa-datorinteraktion.
    Eriksson, Elina
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Människa-datorinteraktion.
    Gulliksen, Jan
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Människa-datorinteraktion.
    Kavathatzopoulos, Iordanis
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Människa-datorinteraktion.
    Sandblad, Bengt
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Matematisk-datavetenskapliga sektionen, Institutionen för informationsteknologi, Människa-datorinteraktion.
    Användbara IT-stöd: En utvärdering av ett forskningsprojekt vid CSN, Centrala studiestödsnämnden2008Rapport (Annet vitenskapelig)
    Abstract [sv]

    Utvecklingsrådet för den statliga sektorn har tagit ett initiativ för att stödja myndigheternas arbete med att förbättra arbetsmiljön och sänka sjukfrånvaron. Därför startades programmet Satsa friskt. Programmet ger stöd i form av ekonomiskt bidrag och experthjälp till olika projekt inom statliga myndigheter. Ett av Satsa Friskts insatsområden är Människa IT . Inom detta område har det sedan 2004 bedrivits ett antal olika projekt vid flera statliga verk. Vi har från MDI (avdelningen för människa-datorinteraktion, institutionen för informationsteknologi) vid Uppsala universitet varit mer omfattande inblandad i tre olika sådana projekt: vid CSN, Migrationsverket och SMHI. Syftet och innehållet har varierat en del mellan de olika projekten, men ett huvudsakligt fokus har varit hur man kan se till att de framtida IT-stödda arbetena inom myndigheterna blir effektivare och arbetsmiljön bättre. Genom att bättre beakta användbarhets- och arbetsmiljöaspekter vid kravställande, utveckling och införande av IT-stöd kan man stödja en positiv utveckling av verksamheten som sådan liksom av arbetsinnehåll och arbetsmiljö för den enskilde individen. Resultatet kan då bli effektivare verksamhet, bättre service till kunder och ett hälsosammare och hållbarare arbete för de anställda. Denna rapport beskriver det arbete som under åren 2005-2007 genomförts i samverkan mellan CSN, Centrala studiestödsnämnden, och MDI, Uppsala universitet. Förutom en kort beskrivning av innehållet i det arbete som gjorts inom projektet redovisar denna rapport en utvärdering av resultatet, de lärdomar som vi gjort från projektet, de råd vi kan ge till andra som vill ta del av dessa lärdomar samt en förteckning av de rapporter av olika slag som producerats.

  • 320. Caminis, Argyro
    et al.
    Henrich, Christopher
    Ruchkin, Vladislav
    Yale University.
    Schwab-Stone, Mary
    Martin, Andrés
    Psychosocial predictors of sexual initiation and high-risk sexual behaviors in early adolescence.2007Inngår i: Child and adolescent psychiatry and mental health, ISSN 1753-2000, Vol. 1, nr 1, s. 14-Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: This longitudinal study examined psychosocial factors associated with risky sexual behavior in early adolescence.

    METHODS: Data were collected through a self-report survey, the Social and Health Assessment (SAHA), which was administered in three waves between 2001 and 2003 to a cohort of incoming sixth grade students in the public school system (149 classes at 17 middle and high schools, N = 1,175) of a small northeastern city in the United States.We first examined whether internalizing and externalizing problems in sixth grade, and the rate of change in these factors during middle school, were predictive of sexual initiation two years later, when most of the sample was in eighth grade. We then assessed whether internalizing and externalizing problems in sixth grade, and the rate of change in these factors during middle school, were predictive of engaging in high risk sexual behavior over the subsequent two years.

    RESULTS: Externalizing factors are more predictive of sexual risk in early adolescence than are internalizing factors. Specifically, substance use and violent delinquency over the course of middle school were associated with higher, while anxiety with lower, sexual initiation rates during middle school. Additionally, increased substance use over the course of middle school was associated with greater likelihood of engaging in high risk sexual behavior.

    CONCLUSION: By identifying particular psychosocial risk factors among young adolescents, the findings of this study have implications for designing multi-dimensional programs aimed at preventing health-compromising sexual behavior among young teens.

  • 321.
    Camurri, A., Lagerlöf, I., & Volpe, G.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Recognizing Emotion from Dance Movement: Comparison of Spectator Recognition and Automated Techniques2003Inngår i: International Journal of Human-Computer Studies, Vol. 59, s. 213-225Artikkel i tidsskrift (Fagfellevurdert)
  • 322. Cannon, Erin N.
    et al.
    Woodward, Amanda L.
    Gredebäck, Gustaf
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    von Hofsten, Claes
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Turek, Colleen
    Action production influences 12-month-old infants' attention to others' actions2012Inngår i: Developmental Science, ISSN 1363-755X, E-ISSN 1467-7687, Vol. 15, nr 1, s. 35-42Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Recent work implicates a link between action control systems and action understanding. In this study, we investigated the role of the motor system in the development of visual anticipation of others actions. Twelve-month-olds engaged in behavioral and observation tasks. Containment activity, infants spontaneous engagement in producing containment actions; and gaze latency, how quickly they shifted gaze to the goal object of anothers containment actions, were measured. Findings revealed a positive relationship: infants who received the behavior task first evidenced a strong correlation between their own actions and their subsequent gaze latency of anothers actions. Learning over the course of trials was not evident. These findings demonstrate a direct influence of the motor system on online visual attention to others actions early in development.

  • 323.
    Carlbring, P
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Book review of M. M. Antony, S. M. Orsillo, L. Roemer (ed). "Practitioner's Guide to Empirically Based Measures of Anxiety".2002Inngår i: Cognitive Behaviour Therapy, Vol. 31, s. 143-Artikkel, omtale (Annet vitenskapelig)
  • 324.
    Carlbring, P., Forslin, P., Willebrand, M., Ljungstrand, P., Strandlund, C., Ekselius, L., & Andersson, G
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Is the Internet-Administered CIDI-SF Equivalent to a Clinician-Administered SCID-Interview?2002Inngår i: Cognitive behaviour therapy, Vol. 31, s. 183-189Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The procedural validity of the Composite International Diagnostic Interview - short form (CIDI-SF) administered via an Internet web-page was examined and compared with an in-person interview (Structured Clinical Interview for DSM-IV Axis I Disorders, rese

  • 325.
    Carlbring, P., Gustafsson, H., Ekselius, L., & Andersson, G.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    12-month prevalence of panic disorder with or without agoraphobia in the Swedish general population2002Inngår i: Social Psychiatry and Psychiatric Epidemiology, ISSN 0933-7954, Vol. 37, nr 5, s. 207-211Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective The present study examined the prevalence of panic disorder with or without agoraphobia according to DSM-IV criteria in the Swedish general population. Method Data were obtained by means of a postal survey administrated to 1000 randomly selected

  • 326.
    Carlbring, P., Gustavsson, H., Ekselius, L., & Andersson, G.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    12-month prevalence of panic disorder in the Swedish general population.2002Inngår i: European Psychiatry, Vol. 17, nr Suppl. 1, s. 138-Artikkel i tidsskrift (Fagfellevurdert)
  • 327.
    Carlbring, Per
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Panic! Its Prevalence, Diagnosis and Treatment via the Internet2004Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    As evidenced by several trials, cognitive behavior therapy (CBT) is a highly effective treatment for Panic disorder with or without agoraphobia (PD). However, therapists are short in supply, and patients with agoraphobia may not seek therapy due to fear of leaving their homes or traveling certain distances. A major challenge therefore is to increase the accessibility and affordability of evidence-based psychological treatments.

    This thesis is based on five studies; three treatment studies set up as randomized controlled trails (RCT), one prevalence study, and one study testing the equivalence of an Internet-administered diagnostic assessment tool with a clinician-administered interview.

    Study I showed that the Swedish 12-month PD prevalence is consistent with findings in most other parts of the Western world (2.2%; CI 95% 1.0%-3.4%). There was a significant sex difference, with a greater prevalence for women (3.6%) compared to men (0.7%).

    Study II showed that the validity of the computerized diagnostic interview (CIDI-SF) was generally low. However, the agoraphobia and obsessive-compulsive disorder modules had good specificity and sensitivity, respectively.

    The three RCTs showed, directly or indirectly, that Internet-based self-help is superior to a waiting-list. When 10 individual weekly sessions of CBT for PD was compared with a 10-module self-help program on the Internet, the results suggest that Internet-administered self-help, plus minimal therapist contact via e-mail, is as effective as traditional individual CBT (80% vs. 67% no longer met criteria for panic disorder; composite within-group effect size was Cohen’s d= 0.78 vs. 0.99). One-year follow-up confirmed the results (92% vs. 88% no longer met criteria for panic disorder; d= 0.80 vs. 0.93). The results generally provide evidence to support the continued use and development of Internet-distributed self-help programs.

    Delarbeid
    1. 12-month prevalence of panic disorder with or without agoraphobia in the Swedish general population
    Åpne denne publikasjonen i ny fane eller vindu >>12-month prevalence of panic disorder with or without agoraphobia in the Swedish general population
    2002 Inngår i: Social Psychiatry and Psychiatric Epidemiology, Vol. 37, nr 5, s. 207-211Artikkel i tidsskrift (Fagfellevurdert) Published
    Identifikatorer
    urn:nbn:se:uu:diva-91567 (URN)
    Tilgjengelig fra: 2004-04-13 Laget: 2004-04-13bibliografisk kontrollert
    2. Is the Internet-administered CIDI-SF Equivalent to a Clinician-administered SCID Interview?
    Åpne denne publikasjonen i ny fane eller vindu >>Is the Internet-administered CIDI-SF Equivalent to a Clinician-administered SCID Interview?
    Vise andre…
    2002 Inngår i: Cognitive Behaviour Therapy, Vol. 31, nr 4, s. 183-189Artikkel i tidsskrift (Fagfellevurdert) Published
    Identifikatorer
    urn:nbn:se:uu:diva-91568 (URN)
    Tilgjengelig fra: 2004-04-13 Laget: 2004-04-13 Sist oppdatert: 2016-01-19bibliografisk kontrollert
    3. Treatment of panic disorder via the Internet: A randomized trial of a self-help program
    Åpne denne publikasjonen i ny fane eller vindu >>Treatment of panic disorder via the Internet: A randomized trial of a self-help program
    Vise andre…
    2001 (engelsk)Inngår i: Behavior Therapy, ISSN 0005-7894, E-ISSN 1878-1888, Vol. 32, nr 4, s. 751-764Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    This controlled study, evaluated an Internet-delivered self-help program plus minimal therapist contact via e-mail for people suffering front panic disorder. Out of the 500 individuals screened using the self-administered diagnostic instrument Composite International Diagnostic Interview in shortened form (World Health Organization, 1999), 41 fulfilled the inclusion criteria. These participants were randomized to either treatment via the Internet or to a waiting-list control. The main components of the treatment were psychoeducation. breathing retraining, cognitive restructuring, interoceptive exposure. in vivo exposure, and relapse prevention. From pre- to post- test self-help, participants improved significantly more on almost all dimensions. The results from this experiment generally provide evidence for the continued use and development of self-help programs for panic disorder distributed via the Internet.

    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-91569 (URN)10.1016/S0005-7894(01)80019-8 (DOI)000175072600009 ()
    Tilgjengelig fra: 2004-04-13 Laget: 2004-04-13 Sist oppdatert: 2017-12-14bibliografisk kontrollert
    4. Treatment of panic disorder via the Internet: a randomized trial of CBT vs. applied relaxation
    Åpne denne publikasjonen i ny fane eller vindu >>Treatment of panic disorder via the Internet: a randomized trial of CBT vs. applied relaxation
    2003 (engelsk)Inngår i: Journal of Behavior Therapy and Experimental Psychiatry, ISSN 0005-7916, E-ISSN 1873-7943, Journal of Behavior Therapy and Experimental Psychiatry, Vol. 34, nr 2, s. 129-140Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    A randomized trial was conducted of two different self-help programs for panic disorder (PD) on the Internet. After confirming the PD-diagnosis with an in-person structured clinical interview for DSM-IV (SCID) interview 22 participants were randomized to either applied relaxation (AR) or a multimodal treatment package based on cognitive behavioral therapy (CBT). Overall, the results suggest that Internet-administered self-help plus minimal therapist contact via e-mail has a significant medium to large effect (Cohen's d=0.71 for AR and d=0.42 for CBT). The results from this study generally provide evidence to support the continued use and development of Internet-distributed self-help programs.

    Emneord
    Internet, Panic disorder, Self-help-techniques, Bibliotherapy
    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-91570 (URN)10.1016/S0005-7916(03)00026-0 (DOI)
    Tilgjengelig fra: 2004-04-13 Laget: 2004-04-13 Sist oppdatert: 2017-12-14bibliografisk kontrollert
    5. Treatment of Panic Disorder: Live Therapy vs. Self-Help via Internet
    Åpne denne publikasjonen i ny fane eller vindu >>Treatment of Panic Disorder: Live Therapy vs. Self-Help via Internet
    Vise andre…
    2005 (engelsk)Inngår i: Behaviour Research and Therapy, ISSN 0005-7967, E-ISSN 1873-622X, Vol. 43, nr 10, s. 1321-1333Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    A randomized trial was conducted comparing 10 individual weekly sessions of cognitive behaviour therapy for panic disorder (PD) with or without agoraphobia with a 10-module self-help program on the Internet. After confirming the PD diagnosis with an in-person structured clinical interview (SCID) 49 participants were randomized. Overall, the results suggest that Internet-administered self-help plus minimal therapist contact via e-mail can be equally effective as traditional individual cognitive behaviour therapy. Composite within-group effect sizes were high in both groups, while the between-group effect size was small (Cohen's d=16). One-year follow-up confirmed the results, with a within-group effect size of Cohen's d=0.80 for the Internet group and d=0.93 for the live group. The results from this study generally provide evidence to support the continued use and development of Internet-distributed self-help programs.

    Emneord
    Internet, Panic disorder, Self-help techniques, Bibliotherapy
    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-91571 (URN)10.1016/j.brat.2004.10.002 (DOI)
    Tilgjengelig fra: 2004-04-13 Laget: 2004-04-13 Sist oppdatert: 2017-12-14
  • 328. Carlbring, Per
    et al.
    Bergman, L
    Furmark, Tomas
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Andersson, Gerhard
    Long term follow-up of Internet-based treatment of social phobia.2007Inngår i: Abstract from the third meeting of the International Society for Research on Internet Interventions, 2007, s. 8-Konferansepaper (Annet vitenskapelig)
  • 329. Carlbring, Per
    et al.
    Bergman, L
    Furmark, Tomas
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Andersson, Gerhard
    Långtidseffekter av Internetbaserad KBT vid social fobi2007Inngår i: Svenska Läkaresällskapets Riksstämma, 2007, s. 94-Konferansepaper (Annet vitenskapelig)
  • 330.
    Carlbring, Per
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Björnstjerna, Eva
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Bergström, Anna F.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Waara, Johan
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Andersson, Gerhard
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Applied relaxation: an experimental analogue study of therapist vs. computer administration2007Inngår i: Computers in human behavior, ISSN 0747-5632, E-ISSN 1873-7692, Vol. 23, nr 1, s. 2-10Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    This experimental analog component study compared two ways of administrating relaxation, either via a computer or by a therapist. The second phase of applied relaxation was used, which is called "release-only relaxation". Sixty participants from a student population were randomized to one of three groups: computer-administered relaxation, therapist-administered relaxation, or a control group in which participants surfed on the Internet. Outcome was measures using psycho-physiological responses and self-report. Objective psychophysiological data and results on the subjective visual analogue scale suggest that there was no difference between the two forms of administration. Both experimental groups became significantly more relaxed than the control group that surfed on the Internet. Practical applications and future directions are discussed.

  • 331. Carlbring, Per
    et al.
    Brunt, Sara
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Bohman, Susanne
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Austin, David
    Richards, Jeffrey
    Öst, Lars-Göran
    Andersson, Gerhard
    Internet vs. paper and pencil administration of questionnaires commonly used in panic/agoraphobia research2007Inngår i: Computers in human behavior, ISSN 0747-5632, E-ISSN 1873-7692, Vol. 23, nr 3, s. 1421-1434Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    The aim of this study was to investigate the psychometric properties of Internet administered questionnaires used in panic research. Included were 494 people who had registered for an Internet-based treatment program for panic disorder (PD). Participants were randomly assigned to fill in the questionnaires either on the Internet or the paper-and-pencil versions, and then to fill in the same questionnaires again the next day using the other format. The questionnaires were the body sensations questionnaire [BSQ; Chambless, D. L., Caputo, G. C., Bright, P., & Gallagher, R. (1984). Assessment of fear of fear in agoraphobics: the body sensations questionnaire and the agoraphobic cognitions questionnaire. Journal of Consulting and Clinical Psychology, 52, 1090-1097], agoraphobic cognitions questionnaire [ACQ; Chambless, D. L., Caputo, G. C., Bright, P., & Gallagher, R. (1984). Assessment of fear of fear in agoraphobics: the body sensations questionnaire and the agoraphobic cognitions questionnaire. Journal of Consulting and Clinical Psychology, 52, 1090-1097], mobility inventory [MI; Chambless, D. L., Caputo, G., Jasin, S., Gracely, E. J., & Williams, C. (1985). The mobility inventory for agoraphobia. Behaviour Research and Therapy, 23, 35-44], beck anxiety inventory [BAI; Beck, A. T., Epstein, N., Brown, G., & Steer, R. A. (1988). An inventory for measuring clinical anxiety: psychometric properties. Journal of Consulting and Clinical Psychology, 56, 893-897], beck depression inventory 11 [Beck, A. T., & Steer, R. A. (1996). Beck Depression Inventory, Manual, Svensk version (Swedish version). Fagernes, Norway: Psykologiforlaget, AB], quality of life inventory [QOLI; Frisch, M. B., Cornell, J., Villanueva, M., & Retzlaff, P. J. (1992). Clinical validation of the quality of life inventory. A measure of life satisfaction for use in treatment planning and outcome assessment. Psychological Assessment, 4, 92-101], and montgomery angstrom sberg depression rating scale [MADRS; Svanborg, P., & angstrom sberg, M. (1994). A new self-rating scale for depression and anxiety states based on the comprehensive psychopathological rating scale. ACTA Psychiatrica Scandinavica, 89, 21-28]. Results showed largely equivalent psychometric properties for the two administration formats (Cronbach's alpha between 0.79 and 0.95). The results also showed high and significant correlations between the Internet and the paper-and-pencil versions. Analyses of order effects showed an interaction effect for the BSQ and the MI (subscale Accompanied), a main effect was identified for ACQ, MI-Alone, BAI and BDIII. However, in contrast to previous research, the Internet version did not consistently generate higher scores and effect sizes for the differences were generally low. Given the presence of an interaction effect, we recommend that the administration format should be stable in research across measurement points. Finally, the findings suggest that Internet versions of questionnaires used in PD research can be used with confidence.

  • 332.
    Carlbring, Per
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Ekselius, Lisa
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
    Andersson, Gerhard
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Treatment of panic disorder via the Internet: a randomized trial of CBT vs. applied relaxation2003Inngår i: Journal of Behavior Therapy and Experimental Psychiatry, ISSN 0005-7916, E-ISSN 1873-7943, Journal of Behavior Therapy and Experimental Psychiatry, Vol. 34, nr 2, s. 129-140Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    A randomized trial was conducted of two different self-help programs for panic disorder (PD) on the Internet. After confirming the PD-diagnosis with an in-person structured clinical interview for DSM-IV (SCID) interview 22 participants were randomized to either applied relaxation (AR) or a multimodal treatment package based on cognitive behavioral therapy (CBT). Overall, the results suggest that Internet-administered self-help plus minimal therapist contact via e-mail has a significant medium to large effect (Cohen's d=0.71 for AR and d=0.42 for CBT). The results from this study generally provide evidence to support the continued use and development of Internet-distributed self-help programs.

  • 333. Carlbring, Per
    et al.
    Nordgren, Lise Bergman
    Furmark, Tomas
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Andersson, Gerhard
    Long-term outcome of Internet-delivered cognitive-behavioural therapy for social phobia: a 30-month follow-up2009Inngår i: Behaviour Research and Therapy, ISSN 0005-7967, E-ISSN 1873-622X, Vol. 47, nr 10, s. 848-850Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Internet-delivered guided cognitive behaviour therapy for social anxiety disorder has been found to generate promising short-term results, up to one year posttreatment. No study has however documented longer follow-up periods. In this 30-month follow-up we contacted 57 participants from the original study of which 77.2% (44/57) responded to the Internet-administered outcome measures and 66.7% (38/57) completed a telephone interview. Results showed large pretreatment to follow-up within-group effect sizes for the primary outcome measures (Cohen's d 1.10-1.71), and a majority (68.4%; 26/38) reported improvements in the interview. The findings suggest that the long-term effects seen in previous live treatment CBT trials can occur in Internet-delivered treatment as well.

  • 334.
    Carlbring, Per
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Westling, Bengt E.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Andersson, Gerhard
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    A review of published self-help books for panic disorder2000Inngår i: Scandinavian Journal of Behaviour Therapy, ISSN 0284-5717, Vol. 29, nr 1, s. 5-13Artikkel, forskningsoversikt (Fagfellevurdert)
    Abstract [en]

    This brief review of 14 self-help books on panic disorder compares: target group, treatment time, included components, existence of structured exercises, and whether or not daily record-keeping is encouraged. Six of the books cover all components deemed necessary for a multimodal cognitive-behavioral treatment package, and five of these are recommended. The reviews are followed by a brief summary of published bibliotherapy studies in which a selection of the books has been used. The results of these studies suggest that bibliotherapy is effective, with an effect size ranging from d = 0.5 to d = 1.5.

  • 335.
    Carlsson, Tommy
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Kukkola, Laura
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Ljungman, Lisa
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa.
    Hovén, Emma
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    von Essen, Louise
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Psychological distress in parents of children treated for cancer: An explorative study2019Inngår i: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 14, nr 6, artikkel-id e0218860Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objective

    To explore psychological distress experienced by parents who express a need for psychotherapy after curative treatment for their child’s cancer.

    Methods

    15 parents (eight mothers and seven fathers) of children treated for cancer (median time since end of curative treatment: two years) were recruited via a pediatric oncology center. Each parent was interviewed twice and data was analyzed with inductive latent qualitative content analysis.

    Results

    Two overarching themes emerged. One theme, An unfamiliar and frightening situation during treatment, portrayed experiences during the treatment period, and included the sub-themes Initial reactions to the uncontrollable situation, Adjustment to the situation, and Focus on supporting the child. Another theme, Emotional struggles after end of curative treatment, portrayed experiences following curative treatment, and included the sub-themes Transitioning back to life as it was before the diagnosis, Emotional scars, Uncontrollable fears and worries of diseases, and New perspectives on life.

    Conclusions

    Parents of children with cancer experience existential, physical, psychological, and social struggles. They describe an unstable situation after diagnosis and having focused their attention towards protecting their child during treatment. After the end of curative treatment, they experience challenges with transitioning back to life as it was before the diagnosis and dealing with their own emotional scars and fears related to the child’s cancer. The findings indicate an unmet need for psychological support among parents of children treated for cancer.

  • 336.
    Carlsson, Tommy
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Mattsson, Elisabet
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård. Ersta Skondal Univ Coll, Dept Hlth Care Sci, SE-10061 Stockholm, Sweden.
    Emotional and cognitive experiences during the time of diagnosis and decision-making following a prenatal diagnosis: a qualitative study of males presented with congenital heart defect in the fetus carried by their pregnant partner2018Inngår i: BMC Pregnancy and Childbirth, ISSN 1471-2393, E-ISSN 1471-2393, Vol. 18, artikkel-id 26Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND:

    Expectant fathers consider the second-trimester obstetric ultrasound examination as an important step towards parenthood, but are ill prepared for a detection of a fetal anomaly. Inductive research is scarce concerning their experiences and needs for support. Consequently, the aim of this study was to explore the emotional and cognitive experiences, during the time of diagnosis and decision-making, among males presented with congenital heart defect in the fetus carried by their pregnant partner.

    METHODS:

    Twelve expectant fathers were consecutively recruited through two tertiary referral centers for fetal cardiology in Sweden, after they had been presented with a prenatal diagnosis of congenital heart defect in the fetus carried by their pregnant partner. The respondents were interviewed via telephone, and the interviews were analyzed using inductive qualitative content analysis.

    RESULTS:

    The respondents experienced an intense emotional shock in connection with detection. However, they set their own needs aside to attend to the supportive needs of their pregnant partner, and stressed the importance of an informed joint decision regarding whether to continue or terminate the pregnancy. When terminating the pregnancy, they experienced a loss of a wanted child, an emotionally intense termination procedure, needs of support neglected by professionals, and worries about the risk of recurrence in future pregnancies. When continuing the pregnancy, they tried to keep a positive attitude about the coming birth, but were simultaneously worried about the postnatal situation.

    CONCLUSIONS:

    The findings illustrate the importance of inclusive care and adequate follow-up routines for both expectant parents following a prenatal diagnosis. This includes the initial emotional shock, the decisional process, and depending on decision reached, the termination or continuation of the pregnancy. Expectant fathers presented with a fetal anomaly need adequate follow-up routines to address worries about risk of recurrence in future pregnancies and worries about the postnatal situation.

  • 337.
    Carlström, Anders
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten.
    Policy capturing in target selection1996Doktoravhandling, monografi (Annet vitenskapelig)
  • 338.
    Casey, Máire-Bríd
    et al.
    Univ Coll Dublin, Sch Publ Hlth Physiotherapy & Sports Sci, Hlth Sci Bldg, Dublin, Ireland.
    Smart, Keith
    St Vincents Univ Hosp, Physiotherapy Dept, Elm Pk, Dublin, Ireland.
    Segurado, Ricardo
    Univ Coll Dublin, Sch Publ Hlth Physiotherapy & Sports Sci, Hlth Sci Bldg, Dublin, Ireland.
    Hearty, Conor
    Mater Misericordiae Univ Hosp, Dept Pain Med, Eccles St, Dublin, Ireland.
    Gopal, Hari
    Mater Misericordiae Univ Hosp, Dept Pain Med, Eccles St, Dublin, Ireland.
    Lowry, Damien
    Mater Misericordiae Univ Hosp, Psychol Dept, Eccles St, Dublin, Ireland.
    Flanagan, Dearbhail
    Mater Misericordiae Univ Hosp, Physiotherapy Dept, Eccles St, Dublin, Ireland.
    McCracken, Lance
    Kings Coll London, Inst Psychiat Psychol & Neurosci, Psychol Dept, London, England.
    Doody, Catherine
    Univ Coll Dublin, Sch Publ Hlth Physiotherapy & Sports Sci, Hlth Sci Bldg, Dublin, Ireland.
    Exercise combined with Acceptance and Commitment Therapy (ExACT) compared to a supervised exercise programme for adults with chronic pain: study protocol for a randomised controlled trial2018Inngår i: Trials, ISSN 1745-6215, E-ISSN 1745-6215, Vol. 19, artikkel-id 194Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Background: Acceptance and Commitment Therapy (ACT) is a form of cognitive behavioural therapy, which may be beneficial for people with chronic pain. The approach aims to enhance daily functioning through increased psychological flexibility. Whilst the therapeutic model behind ACT appears well suited to chronic pain, there is a need for further research to test its effectiveness in clinical practice, particularly with regards to combining ACT with physical exercise.

    Methods/design: This prospective, two-armed, parallel-group, single-centre randomised controlled trial (RCT) will assess the effectiveness of a combined Exercise and ACT programme, in comparison to supervised exercise for chronic pain. One hundred and sixty patients, aged 18 years and over, who have been diagnosed with a chronic pain condition by a physician will be recruited to the trial. Participants will be individually randomised to one of two 8-week, group interventions. The combined group will take part in weekly psychology sessions based on the ACT approach, in addition to supervised exercise classes led by a physiotherapist. The control group will attend weekly supervised exercise classes but will not take part in an ACT programme. The primary outcome will be pain interference at 12-week follow-up, measured using the Brief Pain Inventory-Interference Scale. Secondary outcomes will include self-reported pain severity, self-perception of change, patient satisfaction, quality of life, depression, anxiety and healthcare utilisation. Treatment process measures will include self-efficacy, pain catastrophising, fear avoidance, pain acceptance and committed action. Physical activity will be measured using Fitbit ZipTM activity trackers. Both groups will be followed up post intervention and again after 12 weeks. Estimates of treatment effects at follow-up will be based on an intention-to-treat framework, implemented using a linear mixed-effects model. Individual and focus group qualitative interviews will be undertaken with a purposeful sample of participants to explore patient experiences of both treatments.

    Discussion: To our knowledge, this will be the first RCT to examine whether combining exercise with ACT produces greater benefit for patients with chronic pain, compared to a standalone supervised exercise programme.

    Trial registration: www.ClinicalTrials.gov, ID: NCT03050528. Registered on 13 February 2017.

  • 339. Cassibba, Rosalinda
    et al.
    Granqvist, Pehr
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Constantini, Alessandro
    Gatto, Sergio
    Attachment and God representations among lay Catholics, priests, and religious: a matched comparison study based on the Adult Attachment Interview2008Inngår i: Developmental Psychology, ISSN 0012-1649, E-ISSN 1939-0599, Vol. 44, nr 6, s. 1753-1763Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Based on the idea that believers' perceived relationships with God develop from their attachment-related experiences with primary caregivers, the authors explored the quality of such experiences and their representations among individuals who differed in likelihood of experiencing a principal attachment to God. Using the Adult Attachment Interview (AAI), they compared attachment-related experiences and representations in a group of 30 Catholic priests and religious with a matched group of lay Catholics and with the worldwide normal distribution of AAI classifications. They found an overrepresentation of secure-autonomous states regarding attachment among those more likely to experience a principal attachment to God (i.e., the priests and religious) compared with the other groups and an underrepresentation of unresolved-disorganized states in the two groups of Catholics compared with the worldwide normal distribution. Key findings also included links between secure-autonomous states regarding attachment and estimated experiences with loving or nonrejecting parents on the one hand and loving God imagery on the other. These results extend the literature on religion from an attachment perspective and support the idea that generalized working models derived from attachment experiences with parents are reflected in believers' perceptions of God.

  • 340.
    Catalano, R
    et al.
    Uppsala universitet, Enheter med anknytning till universitetet, Institutet för bostads- och urbanforskning.
    Hartig, T.
    Communal bereavment and the incidence of very low birthweight in Sweden2001Inngår i: Journal of Health and Social Behaviour, Vol. 42, s. 333-341Artikkel i tidsskrift (Fagfellevurdert)
  • 341.
    Cauchard, Laure
    et al.
    Univ Montreal, Dept Sci Biol, Bur D221, Pavillon Marie Victorin,CP 6128,Succ Ctr Ville, Montreal, PQ H3C 3J7, Canada..
    Angers, Bernard
    Univ Montreal, Dept Sci Biol, Bur D221, Pavillon Marie Victorin,CP 6128,Succ Ctr Ville, Montreal, PQ H3C 3J7, Canada..
    Boogert, Neeltje J.
    Univ Oxford, Dept Zool, Edward Grey Inst, Oxford, England..
    Doligez, Blandine
    Uppsala universitet, Teknisk-naturvetenskapliga vetenskapsområdet, Biologiska sektionen, Institutionen för ekologi och genetik, Zooekologi. Univ Lyon 1, CNRS, UMR 5558, Dept Biometry & Evolutionary Biol, Villeurbanne, France..
    Effect of an anti-malaria drug on behavioural performance on a problem-solving task: An experiment in wild great tits2016Inngår i: Behavioural Processes, ISSN 0376-6357, E-ISSN 1872-8308, Vol. 133, s. 24-30Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Malaria parasites have been shown to decrease host fitness in several species in the wild and their detrimental effects on host cognitive ability are well established in humans. However, experimental demonstrations of detrimental effects on non-human host behaviour are currently limited. In this study, we experimentally tested whether injections of an anti-malaria drug affected short-term behavioural responses to a problem-solving task during breeding in a wild population of great tits (Parus major) naturally infected with malaria. Adult females treated against malaria were more active than control females, even though they were not more likely to solve the task or learn how to do so, suggesting that energetic constraints could shape differences in some behaviours while changes in cognitive performances might require more time for the neural system to recover or may depend mainly on infection at the developmental stage. Alternatively, parasite load might be a consequence, rather than a cause, of inter individual variation in cognitive performance. These results also suggest that inter-individual as well as inter-population differences in some behavioural traits may be linked to blood parasite load.

  • 342.
    Cernvall, Martin
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Självhjälp med e-poststöd vid full och partiell anorexia nervosa: preliminära resultat från en randomiserad kontrollerad studie2007Independent thesis Advanced level (degree of Master (Two Years)), 20 poäng / 30 hpOppgave
    Abstract [sv]

    Anorexia nervosa är ett allvarligt tillstånd med hög dödlighet i långtidsuppföljningar. Trots detta finns i dagsläget ingen tydlig evidens vad gäller val av metod eller effektivitet när det gäller behandling för denna problematik. Föreliggande uppsats rapporterar preliminära resultat från en randomiserad kontrollerad studie av självhjälp med e-poststöd för individer med full och partiell anorexia nervosa. Syftet var att undersöka huruvida en behandling i självhjälpsformat som bygger på rekommenderade riktlinjer för vård av anorexia nervosa samt acceptance and commitment therapy är effektiv med avseende på beteende-, attityd- ochpersonlighetsvariabler relaterade till ätstörningsproblematik samt generella variabler som depression, självkänsla, tillfredställelse med livet och social anpassning. Under tidsperioden inkluderades 15 deltagare i studien och randomiserades till behandling(N=7) eller väntelista (N=8). Deltagare genomgick EDE-intervju före och efter behandling respektive väntelista samt svarade på en rad självskattningsformulär. Behandling respektive väntelista pågick under 12 veckor där deltagare i behandlingsgruppen arbetade på egen handmed ett nyskrivet självhjälpsmaterial med stöd via e-post från en kontaktperson.”Intent-to-treat”-analyser visade på enstaka signifikanta förbättringar i inomgruppsjämförelser mellan för- och eftermätning för behandlingsgruppen på attitydvariabler. Deltagarna i behandlingsgruppen försämrades dock signifikant på den generella variabeln social anpassning. Beräkning av kliniskt signifikanta förbättringar visade på enstaka förbättringar för enskilda deltagare. Ingen deltagare rörde sig ur en ätstörningsdiagnos men två deltagare i behandlingsgruppen ökade i vikt. Ingen deltagare i väntelistgruppen ökade lika mycket, istället gick tre ner motsvarande vikt. Slutsatserna är att resultaten är för preliminära för att med säkerhet kunna uttala sig ombehandlingsformatets effektivitet för denna problematik. Data från fler deltagare samt uppföljningsmätningar behövs för att kunna besvara frågeställningarna på ett adekvat sätt.

  • 343.
    Cernvall, Martin
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap.
    Symptoms of Posttraumatic Stress in Parents of Children on Cancer Treatment: Factor Structure, Experiential Avoidance, and Internet-based Guided Self-help2014Doktoravhandling, med artikler (Annet vitenskapelig)
    Abstract [en]

    Having a child diagnosed with cancer is stressful and many parents of children on treatment for cancer report symptoms of posttraumatic stress (PTSS). The overall purpose was to, among parents of children on treatment for cancer, investigate the factor structure of PTSS; investigate the relationships between experiential avoidance (EA), rumination, PTSS and depression; and to develop, test, and evaluate a guided self-help intervention provided via the internet.

    In a longitudinal study with three assessments (n = 249-203) results indicated that a four-factor solution of PTSS including the factors re-experiencing, avoidance, dysphoria, and hyper-arousal provided best fit and that the pattern and size of factor loadings were equivalent across the three assessments (Study I). In a case study with pre-, post-, and follow-up assessments a guided self-intervention was well received with clinical significant and reliable improvements in PTSS, depression, and quality of life (Study II). Furthermore, in cross-sectional analyses (n = 79) EA and rumination were positively associated with PTSS and depression and provided incremental explanation in depression while controlling for demographic characteristics, anxiety, and PTSS. In longitudinal analyses (n = 20), EA but not rumination predicted PTSS and depression while controlling for initial levels (Study III). Finally, in a randomized controlled trial with parents fulfilling the modified symptom criteria on the PTSD-Checklist allocated to guided self-help via the internet (n = 31) or to a wait-list control condition (n = 27) there was a significant intervention effect with a large effect size for the primary outcome PTSS. Similar results were observed for the secondary outcomes depression and anxiety, but not for EA and rumination. Exploratory analyses suggested that the relationships between EA and PTSS and between EA and depression were weakened in the intervention group (Study IV).

    The studies included in the current thesis suggest that a four-factor solution should be used when assessing PTSS in parents of children on cancer treatment. Furthermore, rumination and EA in particular seem to be important constructs to consider when understanding PTSS and depression in this population. Finally, guided self-help via the internet shows promise in reducing PTSS and depression among parents of children on cancer treatment who report a high level of PTSS.

    Delarbeid
    1. The factor structure of traumatic stress in parents of children with cancer: A longitudinal analysis
    Åpne denne publikasjonen i ny fane eller vindu >>The factor structure of traumatic stress in parents of children with cancer: A longitudinal analysis
    2012 (engelsk)Inngår i: Journal of Pediatric Psychology, ISSN 0146-8693, E-ISSN 1465-735X, Vol. 37, nr 4, s. 448-457Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    Objectives To determine the factor structure of posttraumatic stress symptoms (PTSS) and assess its stability over time among parents of children diagnosed with cancer. 

    Methods  Parents of children with cancer included in a longitudinal study completed the posttraumatic stress disorder (PTSD) Checklist–Civilian Version 2 weeks (n = 249) and 2 (n = 234) and 4 (n = 203) months after their child's diagnosis. Confirmatory factor analysis (CFA) was used to assess 3 models of the underlying dimensions of PTSD and invariance tests were used to assess stability over time. 

    Results  A longitudinal CFA with the factors reexperiencing, avoidance, dysphoria, and hyperarousal provided best fit to the data. Invariance testing suggested that the pattern and size of loadings were equivalent across the three assessments. 

    Discussions Findings tentatively suggest that PTSS among parents of children with cancer consist of four factors. Implications for research and clinical practice are discussed.

    Emneord
    assessment, cancer and oncology, children, longitudinal research, parent stress, psychosocial functioning
    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-161720 (URN)10.1093/jpepsy/jsr105 (DOI)000303330600009 ()
    Merknad

    Erratum in: Journal of Pediatric Psychology (2013), 38(2): 237–240. doi: 10.1093/jpepsy/jss125

    Tilgjengelig fra: 2011-12-15 Laget: 2011-11-16 Sist oppdatert: 2017-12-08bibliografisk kontrollert
    2. Guided self-help as intervention for traumatic stress in parents of children with cancer: Conceptualization, intervention strategies, and a case study
    Åpne denne publikasjonen i ny fane eller vindu >>Guided self-help as intervention for traumatic stress in parents of children with cancer: Conceptualization, intervention strategies, and a case study
    2013 (engelsk)Inngår i: Journal of psychosocial oncology, ISSN 0734-7332, E-ISSN 1540-7586, Vol. 31, nr 1, s. 13-29Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    Being a parent of a child diagnosed with cancer poses an enormous stressor. Indeed, several parents have difficulties adjusting to such a situation and react with symptoms of traumatic stress, depression, and reduced quality of life. However, there is little conceptual work on behavioral mechanisms that contribute to suboptimal adaptation in these parents. The authors present a conceptualization in which experiential avoidance and rumination are suggested to contribute to increased levels of traumatic stress and suboptimal adaption. Based on this conceptualization, a recently developed intervention for parents of children with cancer, in the form of guided self-help, is presented. Finally, the authors present a successful case study as an example of the application of this intervention. Clinical implications and suggestions for future research are discussed.

    Emneord
    Intervention, Parents, Pediatric oncology, Self-help, Traumatic stress
    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-187322 (URN)10.1080/07347332.2012.741095 (DOI)000315983500002 ()
    Tilgjengelig fra: 2012-12-05 Laget: 2012-12-05 Sist oppdatert: 2017-12-07bibliografisk kontrollert
    3. Experiential Avoidance and Rumination in Parents of Children on Cancer Treatment: Relationships with Posttraumatic Stress Symptoms and Symptoms of Depression
    Åpne denne publikasjonen i ny fane eller vindu >>Experiential Avoidance and Rumination in Parents of Children on Cancer Treatment: Relationships with Posttraumatic Stress Symptoms and Symptoms of Depression
    Vise andre…
    2016 (engelsk)Inngår i: Journal of clinical psychology in medical settings, ISSN 1068-9583, E-ISSN 1573-3572, Vol. 23, nr 1, s. 67-76Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    We conducted a cross-sectional survey study to investigate whether there is a relationship between experiential avoidance (EA), rumination, post-traumatic stress symptoms (PTSS), and symptoms of depression, in parents of children on cancer treatment. Data from 79 parents (55 mothers) of 79 children with a median of three months since their cancer diagnosis were included in cross-sectional analyses. EA and rumination were positively correlated with PTSS and symptoms of depression. EA and rumination did not provide incremental explained variance in PTSS over and above that explained by symptoms of depression, while controlling for symptoms of anxiety and demographic characteristics. However, EA and rumination provided incremental explained variance in symptoms of depression over and above that explained by PTSS, while controlling for symptoms of anxiety and demographic characteristics. Rumination and EA are important constructs in the understanding of PTSS and symptoms of depression in parents of children on cancer treatment. Future research should delineate the temporal relationships between these constructs.

    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-234500 (URN)10.1007/s10880-015-9437-4 (DOI)000371621600007 ()26462676 (PubMedID)
    Konferanse
    Conference of the Association-of-Psychologists-in-Academic-Health-Centers (APAHC), FEB, 2015, Atlanta, GA, USA
    Forskningsfinansiär
    Swedish Research Council, K2008-70X-20836-01-3, K2011-70X-20836-04-4Swedish Cancer Society, 2010/276Swedish Childhood Cancer Foundation, PROJ08/010, PRO12/028
    Merknad

    Tidigare titel: Experiential avoidance and rumination in parents of children on cancer treatment: Relationships with posttraumatic stress symptoms and depression

    Tilgjengelig fra: 2014-10-20 Laget: 2014-10-20 Sist oppdatert: 2017-12-05bibliografisk kontrollert
    4. Internet-based guided self-help for parents of children on cancer treatment: A randomized controlled trial
    Åpne denne publikasjonen i ny fane eller vindu >>Internet-based guided self-help for parents of children on cancer treatment: A randomized controlled trial
    Vise andre…
    2015 (engelsk)Inngår i: Psycho-Oncology, ISSN 1057-9249, E-ISSN 1099-1611, Vol. 24, nr 9, s. 1152-1158Artikkel i tidsskrift (Fagfellevurdert) Published
    Abstract [en]

    Objective

    The aim of the study was to investigate the feasibility and preliminary efficacy of an Internet-based guided self-help intervention for posttraumatic stress symptoms (PTSS) and related symptoms in parents of children on cancer treatment.

    Methods

    Parents of children on cancer treatment, who fulfilled the modified symptom criteria on the PTSD Checklist, were randomly allocated to the intervention or to a wait-list control condition. The intervention group accessed a 10-week guided self-help program via the Internet based on principles from cognitve behavior therapy. The primary outcome PTSS and the secondary outcomes depression and anxiety were assessed by self-report preintervention and postintervention.

    Results

    Seven hundred forty-seven parents were approached and informed about the study, 92 were assessed for eligibility, and 58 were included and randomized to the intervention (n = 31) or wait list (n  = 27). Eightteen participants completed the intervention. Intention-to-treat analyses indicated a significant effect of the intervention on PTSS with a large between-group effect size at postassessment (Cohen's d = 0.88). The intervention group reported reductions in PTSS with a large within-group effect size (d = 1.62) compared with a minimal reduction in the wait-list group (d  = 0.09). There was a significant intervention effect on depression and anxiety and reductions in the intervention group with large within-group effect sizes (d = 0.85–1.09).

    Conclusions

    Findings indicate a low enrollment rate and considerable attrition but also that Internet-based guided self-help shows promise for parents of children on cancer treatment who report a high level of PTSS and would like to take part in an Internet-based intervention.

    HSV kategori
    Identifikatorer
    urn:nbn:se:uu:diva-234503 (URN)10.1002/pon.3788 (DOI)000360992900022 ()25728688 (PubMedID)
    Forskningsfinansiär
    Swedish Research Council, K2008-70X-20836-01-3 K2011-70X-20836-04-4Swedish Cancer Society, 2010/276Swedish Childhood Cancer Foundation, PROJ08/010 PRO12/028
    Tilgjengelig fra: 2014-10-20 Laget: 2014-10-20 Sist oppdatert: 2017-12-05bibliografisk kontrollert
  • 344.
    Cernvall, Martin
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Kunskapscentrum för katastrofpsykiatri. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård.
    Bergh Johannesson, Kerstin
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Kunskapscentrum för katastrofpsykiatri. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
    Arnberg, Filip K
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm, Kunskapscentrum för katastrofpsykiatri. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
    The Interdependency in Development of Prolonged Grief and Posttraumatic Stress in Individuals Exposed to a Natural Disaster and who Lost a Close Relative: A Latent Growth with Dual Processes Approach2015Konferansepaper (Fagfellevurdert)
  • 345.
    Cernvall, Martin
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Psykosocial onkologi och stödjande vård.
    Carlbring, Per
    Ljungman, Lisa
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Psykosocial onkologi och stödjande vård.
    Ljungman, Gustaf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Pediatrik.
    von Essen, Louise
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård.
    Guided Self-help via the Internet for Parents of Children Recently Diagnosed with Cancer: A Randomized Controlled Trial2014Konferansepaper (Fagfellevurdert)
  • 346.
    Cernvall, Martin
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Carlbring, Per
    Wikman, Anna
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Ljungman, Lisa
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Ljungman, Gustaf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Pediatrik.
    von Essen, Louise
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Forskargrupper (Inst. för kvinnor och barns hälsa), Klinisk psykologi i hälso- och sjukvård.
    Twelve-Month Follow-Up of a Randomized Controlled Trial of Internet-Based Guided Self-Help for Parents of Children on Cancer Treatment2017Inngår i: Journal of Medical Internet Research, ISSN 1438-8871, E-ISSN 1438-8871, Vol. 19, nr 7, artikkel-id e273Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    BACKGROUND: A substantial proportion of parents of children on cancer treatment report psychological distress such as symptoms of post-traumatic stress (PTSS), depression, and anxiety. During their child's treatment many parents also experience an economic burden.

    OBJECTIVE: The aim of this study was to evaluate the long-term efficacy of Internet-based guided self-help for parents of children on cancer treatment.

    METHODS: This study was a parallel randomized controlled trial comparing a 10-week Internet-based guided self-help program, including weekly support from a therapist via encrypted email, with a wait-list control condition. The intervention was based on cognitive behavior therapy (CBT) and focused on psychoeducation and skills to cope with difficult thoughts and feelings. Primary outcome was self-reported PTSS. Secondary outcomes were self-reported symptoms of depression, anxiety, health care consumption, and sick leave during the past month. Outcomes were assessed pre- and postintervention and at 12-month follow-up. Parents of children on cancer treatment were invited by health care personnel at pediatric oncology centers, and parents meeting the modified symptom criteria on the PCL-C were included in the study. Self-report assessments were provided on the Web.

    RESULTS: A total of 58 parents of children on cancer treatment (median months since diagnosis=3) were included in the study (intervention n=31 and control n=27). A total of 18 participants completed the intervention, and 16 participants in each group participated in the 12-month follow-up. Intention-to-treat analyses revealed significant effects in favor of the intervention on the primary outcome PTSS, with large between-group effect sizes at postassessment (d=0.89; 95% CI 0.35-1.43) and at 12-month follow-up (d=0.78; 95% CI 0.25-1.32). Significant effects in favor of the intervention on the secondary outcomes depression and anxiety were also observed. However, there was no evidence for intervention efficacy on health care consumption or sick leave.

    CONCLUSIONS: Using the Internet to provide psychological interventions shows promise as an effective mode of delivery for parents reporting an increased level of PTSS and who consider Internet-based interventions as a viable option. Future research should corroborate these findings and also develop and evaluate interventions and policies that may help ameliorate the economic burden that parents may face during their child's treatment for cancer.

  • 347.
    Cernvall, Martin
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård.
    Hovén, Emma
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård.
    Ljungman, Lisa
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård.
    Ljungman, Gustaf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa.
    Carlbring, Per
    Stockholm Univ, Dept Psychol, S-10691 Stockholm, Sweden.
    von Essen, Louise
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård.
    Posttraumatic stress and attentional bias towards cancer-related stimuli in parents of children recently diagnosed with cancer2016Inngår i: PLoS ONE, ISSN 1932-6203, E-ISSN 1932-6203, Vol. 11, nr 4, artikkel-id e0152778Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Objectives: To investigate whether posttraumatic stress symptoms (PTSS) are related to attentional bias towards cancer-related stimuli among parents of children recently diagnosed with cancer.

    Methods: Sixty-two parents completed questionnaires measuring PTSS, depression, and anxiety and the emotional Stroop task via the Internet. The emotional Stroop task included cancer-related words, cardiovascular disease-related words, and neutral words.

    Results: Participants were split in two groups based on the median of PTSS: High-PTSS and Low-PTSS. There was a significant interaction between word-type and group and a planned contrast test of this interaction indicated that the High-PTSS group had longer response latencies on cancer-related words compared to the other word-type and group combinations.

    Conclusions: Findings suggest that PTSS are related to attentional bias towards cancer-related stimuli among parents of children recently diagnosed with cancer. Implications of this finding for the understanding of PTSS in this population, future research, and clinical practice are discussed.

  • 348.
    Cernvall, Martin
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Psykiatri, Akademiska sjukhuset.
    Ljungman, Lisa
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa.
    Wikman, Anna
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa.
    Carlbring, Per
    Stockholm Univ, Stockholm, Sweden..
    Ljungman, Gustaf
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa, Pediatrik.
    von Essén, Louise
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för folkhälso- och vårdvetenskap, Klinisk psykologi i hälso- och sjukvård. Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för kvinnors och barns hälsa. Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Samhällsvetenskapliga fakulteten, Institutionen för psykologi.
    Dimensions of Posttraumatic Stress Symptoms and their Relationships with Depression, Anxiety, and Quality of Life in Parents of Children Recently Diagnosed with Cancer2016Inngår i: Psycho-Oncology, ISSN 1057-9249, E-ISSN 1099-1611, Vol. 25, nr SP. S3, s. 76-76Artikkel i tidsskrift (Annet vitenskapelig)
  • 349.
    Cetrez, Önver
    et al.
    Uppsala universitet, Humanistisk-samhällsvetenskapliga vetenskapsområdet, Teologiska fakulteten, Teologiska institutionen, Religionsbeteendevetenskap, Religionspsykologi.
    Balkir, Nazli
    Department of Psychology, Işık University, Istanbul, Turkey.
    Resilience and Mental Health Risks among Syrian Refugees in Europe: A Cultural Perspective2017Inngår i: ACTA PSYCHOPATHOLOGICA, ISSN 2469-6676, Vol. 5, nr 5, s. 1-4, artikkel-id 65Artikkel i tidsskrift (Fagfellevurdert)
    Abstract [en]

    Dated from 2011, the civil war in Syria has forced more than half of the Syrians to leave their home. This crisis is defined as the world's largest humanitarian tragedy since the World War II. Ransom and kidnap, rape, sexual slavery, brutal executions, disappearances, forced displacement have become regular part of the daily news from the region. As for today, the total number of people in need of humanitarian assistance in Syria has reached 12.2 million, approximately 7.6 million of whom are internally displaced; the largest number of internally displaced persons in any country in the world [1]. Refugees from Syria are now the largest refugee population in the world with more than four million Syrian refugees in neighbouring countries and the larger region, such as Europe. The continuation of multi-sided armed conflict has lead to new cross-border movements of refugees each year, increasing the number of Syrians seeking protection in Europe [2-4].

    In response to the humanitarian needs, many EU countries have received applications from asylum seekers and refugees. The report of UNHCR in 2014 claims 562.680 asylum applications records in 38 European countries, which reflects an increase of 24% in comparison to the same period of 2013 [5,6]. The number of people applying for asylum in the European Union was more than doubled in 2015, reaching a record 1.26 million, according to the EU statistics agency. Syrians accounted for almost a third, with 362,775 people seeking shelter in Europe, followed by Afghans and Iraqis. Since 2016, rapid growth rate of the refugee population has been decelerating slightly [7,8].

    Eurostat [9] reports that the highest number of positive asylum decisions was recorded in Germany, followed by Sweden, France and Italy, the United Kingdom and the Netherlands under the UN's humanitarian resettlement program. Those aforementioned states accounted for 81 % of the total number of acceptances issued in the EU-28 [9,10].

    In conjunction with their educational needs and possibility to work and settlement in the countries of migration, the health situation of the refugees is a large field of concern. A United Nations and Government of Syria joint assessment mission has specified mental health and psychosocial support as one of the most major concerns resulting from the current crisis [11]. In light of this unique set of challenges, there is an ongoing need for information on the mental health issues and culturally appropriate interventions not only for reducing symptoms of psychological distress but also for enhancing qualities of psychological and social wellbeing of this marginalized population. Hence, the specific objectives of the current paper are to: 1) provide basic information on the common mental health problems caused by the crisis; 2) discuss cultural issues in the conceptualizations of mental health problems, resilience enhancing practices and possible expectations about the appropriate healing strategies in order to promote mental health status and psychiatric care of Syrian refugees in Europe.

  • 350.
    Chapman, Colin Daniel
    et al.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Funktionell farmakologi.
    Benedict, Christian
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Funktionell farmakologi.
    Schiöth, Helgi B.
    Uppsala universitet, Medicinska och farmaceutiska vetenskapsområdet, Medicinska fakulteten, Institutionen för neurovetenskap, Funktionell farmakologi.
    Experimenter gender and replicability in science2018Inngår i: Science Advances, E-ISSN 2375-2548, Vol. 4, nr 1, artikkel-id e1701427Artikkel, forskningsoversikt (Fagfellevurdert)
    Abstract [en]

    There is a replication crisis spreading through the annals of scientific inquiry. Although some work has been carried out to uncover the roots of this issue, much remains unanswered. With this in mind, this paper investigates how the gender of the experimenter may affect experimental findings. Clinical trials are regularly carried out without any report of the experimenter's gender and with dubious knowledge of its influence. Consequently, significant biases caused by the experimenter's gender may lead researchers to conclude that therapeutics or other interventions are either overtreating or undertreating a variety of conditions. Bearing this in mind, this policy paper emphasizes the importance of reporting and controlling for experimenter gender in future research. As backdrop, it explores what we know about the role of experimenter gender in influencing laboratory results, suggests possible mechanisms, and suggests future areas of inquiry.

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