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Publications (10 of 92) Show all publications
Aune, A., Jimenez-Diaz, G., Gierman, L. M., Vartdal, G., Berlanga, M. R., Tusoy, J., . . . Darj, E. (2025). Smartphone-based screening of neonatal jaundice in three populations in low and middle-income countries: a cross-sectional study. BMJ Paediatrics Open, 9(1), Article ID e002242.
Open this publication in new window or tab >>Smartphone-based screening of neonatal jaundice in three populations in low and middle-income countries: a cross-sectional study
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2025 (English)In: BMJ Paediatrics Open, E-ISSN 2399-9772, Vol. 9, no 1, article id e002242Article in journal (Refereed) Published
Abstract [en]

Background

Neonatal hyperbilirubinemia (NHB) is a significant cause of morbidity and mortality, particularly in low and middle-income countries (LMICs). Transcutaneous bilirubinometers offer a non-invasive method for assessing NHB but have limited availability due to cost and maintenance requirements. Visual assessment of jaundice is shown to be inaccurate. Smartphone-based technologies have the potential to provide innovative and accessible healthcare solutions. This study aimed to evaluate the Picterus system, a smartphone-based tool for screening of NHB, in three non-Caucasian populations in LMICs.

Methods

Between 2018 and 2022, cross-sectional studies were conducted in three countries: Mexico, Nepal and the Philippines. Newborns meeting the inclusion criteria were recruited, and data on demographic characteristics, skin type and visual assessment of jaundice were collected. Bilirubin levels were measured using both the Picterus system and total serum bilirubin (TSB) analysis. Correlation analyses, Bland-Altman plots and receiver operating characteristic (ROC) curves were used to evaluate the Picterus system.

Results

A total of 416 infants were included in the analysis. The Picterus smartphone system demonstrated a significant positive correlation with TSB levels across all sites (r=0.76). The correlation coefficient was significantly higher in Mexico compared with Nepal and the Philippines. Bland-Altman plots showed limits of agreement ±89.2 µmol/L. Picterus values were underestimated in Mexico, whereas they were overestimated in Nepal and the Philippines. ROC analysis for detection of infants with TSB >225 µmol/L indicated that the Picterus system had higher sensitivity and specificity compared with visual assessment using the Kramer scale.

Discussion

This study shows that the Picterus system can potentially be used in screening for neonatal jaundice in populations with moderate dark skin types. Further studies are needed before the system can be used in clinical practice.

Place, publisher, year, edition, pages
BMJ Publishing Group Ltd, 2025
Keywords
Screening, Jaundice, Neonatology, Information Technology
National Category
Pediatrics
Identifiers
urn:nbn:se:uu:diva-557156 (URN)10.1136/bmjpo-2023-002242 (DOI)001486689500001 ()40345804 (PubMedID)
Available from: 2025-06-02 Created: 2025-06-02 Last updated: 2025-06-02Bibliographically approved
Nechaeva, E., Kharkova, O., Postoev, V., Grjibovski, A. M., Darj, E. & Odland, J. Ø. (2024). Awareness of postpartum depression among midwives and pregnant women in Arkhangelsk, Arctic Russia. Global Health Action, 17(1), Article ID 2354008.
Open this publication in new window or tab >>Awareness of postpartum depression among midwives and pregnant women in Arkhangelsk, Arctic Russia
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2024 (English)In: Global Health Action, ISSN 1654-9716, E-ISSN 1654-9880, Vol. 17, no 1, article id 2354008Article in journal (Refereed) Published
Abstract [en]

Background

Postpartum depression (PPD) affects approximately 17% of the women worldwide with nearly half of all cases going undetected. More research on maternal mental health, particularly among healthcare professionals and pregnant mothers, could help identify PPD risks and reduce its prevalence.

Objective

Given that awareness of PPD is a crucial preventive factor, we studied PPD awareness among midwives and pregnant women in Arkhangelsk, Arctic Russia.

Methods

A qualitative study was conducted using in-depth semi-structured interviews. Midwives and pregnant women were recruited from the women’s clinic of the Arkhangelsk municipal polyclinic. Seven midwives and 12 pregnant mothers were interviewed.

Results

Midwives described limited time for psychological counselling of pregnant women; they reported that their primary focus was on the physiological well-being of women. Pregnant women have expressed a desire for their families to share responsibilities. The participants considered PPD as a mix of psychological and physiological symptoms, and they also highlighted a discrepancy between the expectations of pregnant women and the reality of motherhood. The present study underscored the limited understanding of PPD identification.

Conclusions

The findings suggest that there is a need for increased awareness among midwives and pregnant women regarding PPD. Prevention programs targeting PPD with a specific emphasis on enhancing maternal mental health knowledge are warranted.

Place, publisher, year, edition, pages
Taylor & Francis, 2024
Keywords
Postnatal depression, maternal health, perceptions, pregnant woman, midwife
National Category
Gynaecology, Obstetrics and Reproductive Medicine Nursing
Identifiers
urn:nbn:se:uu:diva-532546 (URN)10.1080/16549716.2024.2354008 (DOI)001237677400001 ()38828500 (PubMedID)
Available from: 2024-06-24 Created: 2024-06-24 Last updated: 2025-02-11Bibliographically approved
Eriksen, I., Rasmussen, E. H., Karmacharya, B., Das, S., Darj, E. & Odland, M. L. (2024). Challenges and possible improvements for healthcare teams at outreach clinics in Nepal: a qualitative study. Global Health Action, 17(1), Article ID 2385177.
Open this publication in new window or tab >>Challenges and possible improvements for healthcare teams at outreach clinics in Nepal: a qualitative study
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2024 (English)In: Global Health Action, ISSN 1654-9716, E-ISSN 1654-9880, Vol. 17, no 1, article id 2385177Article in journal (Refereed) Published
Abstract [en]

Background

All Nepalese citizens have the right to high-quality healthcare services free of charge. To achieve this, healthcare services for the rural population in Nepal need to be improved in terms of personnel, medicines, and medical equipment.

Objectives

To explore challenges and possible improvements healthcare personnel experience when travelling to rural parts of Nepal to provide healthcare.

Method

Data was collected from various health professionals using focus group discussions at Dhulikhel Hospital in Nepal. The data were transcribed and analysed using Systematic text condensation.

Results

Twenty-two professional healthcare personnel participated in five group discussions. Four categories emerged from the collected material: Finding ORC services being underutilised, Wanting to fulfil tasks and do a good job, Facing inadequate resources, and Seeing the need for improved organisation and cooperation. There was consensus that rural clinics are important to maintaining health for the rural population of Nepal. However, there was frustration that the rural population was not benefitting from all available healthcare services due to underutilisation.

Conclusion

Rural healthcare clinics are not utilised appropriately, according to healthcare workers at the rural outreach clinics. Potential ways of overcoming the perceived challenges of underutilising available healthcare services include financial and human resources. The rural population<acute accent>s health awareness needs to be increased, and the work environment for rural healthcare workers needs to be improved. These issues need to be prioritised by the government and policymakers.

Main findings: Outreach clinics in Nepal are perceived as underutilised by health providers.

Added knowledge: Increased awareness among rural people on when to seek healthcare, improved work conditions for health providers and collaboration with other health facilities may strengthen the utilisation of offered care.

Global health impact for policy and action: Updated policies reflecting these Nepalese suggestions on strengthening rural healthcare may be useful and benefit other rural populations in similar settings.

Place, publisher, year, edition, pages
Taylor & Francis, 2024
Keywords
Health providers, Nepal, outreach clinics, perceptions, rural healthcare, qualitative research
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:uu:diva-537017 (URN)10.1080/16549716.2024.2385177 (DOI)001285493800001 ()39109605 (PubMedID)
Available from: 2024-09-12 Created: 2024-09-12 Last updated: 2025-02-20Bibliographically approved
Habtu, T. A., Pembe, A. B., Chiwanga, F., Odland, J. O. & Darj, E. (2024). Women's experience of preterm birth in an East African context: a qualitative study. African Health Sciences, 24(1), 151-162
Open this publication in new window or tab >>Women's experience of preterm birth in an East African context: a qualitative study
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2024 (English)In: African Health Sciences, ISSN 1680-6905, E-ISSN 1729-0503, Vol. 24, no 1, p. 151-162Article in journal (Refereed) Published
Abstract [en]

Background: Approximately 15 million children are born each year prematurely, representing more than 10 percent of all childbirths worldwide. Prematurity is an acute event and the leading cause of death among newborns and children under five. Sixty percent of these premature deaths occur in Sub-Saharan Africa and Southeast Asia.

Objective: The current study aimed to explore and understand women's experiences and perceptions regarding giving birth prematurely at the National Hospital of Muhimbili in Dar es Salaam, Tanzania.

Method: A qualitative method, using Interpretive Phenomenological Analysis approach was chosen to understand and describe the women's experiences. A semi-structured guide was used during the interviews. All interviews were audio-recorded and transcribed verbatim.

Findings: Eight in-depth interviews were conducted. The analysis revealed three superordinate themes: (a) Emotional turmoil: unmet expectations shattering maternal identity, emotional distress, and loss of hope; (b) Adapting to preterm birth and challenges: the unexpected situation, lack of proper care, strenuous breastfeeding routines, and socioeconomic challenges; (c) Significance of proper care and emotional support: good maternal care, mother-to-mother and family support.

Conclusion: This study provided a deeper understanding of women's experiences and perceptions of premature childbirth. The current study indicated the importance of caregivers' awareness of the women's emotional distress, their need to adapt to a sudden unexpected situation, and the necessity of emotional support.

Place, publisher, year, edition, pages
Makerere University, 2024
Keywords
Preterm birth, maternal experiences, Tanzania, Global health
National Category
Nursing Public Health, Global Health and Social Medicine Gynaecology, Obstetrics and Reproductive Medicine
Identifiers
urn:nbn:se:uu:diva-548607 (URN)10.4314/ahs.v24i1.19 (DOI)001393173800010 ()38962353 (PubMedID)2-s2.0-85190479210 (Scopus ID)
Available from: 2025-02-04 Created: 2025-02-04 Last updated: 2025-02-04Bibliographically approved
Okafor, C., Olaniran, A. & Darj, E. (2023). Challenges and recommendations for addressing under-five pneumonia morbidity and mortality in Nigeria. African Health Sciences, 23(2), 193-201
Open this publication in new window or tab >>Challenges and recommendations for addressing under-five pneumonia morbidity and mortality in Nigeria
2023 (English)In: African Health Sciences, ISSN 1680-6905, E-ISSN 1729-0503, Vol. 23, no 2, p. 193-201Article in journal (Refereed) Published
Abstract [en]

Background: Pneumonia is a severe infection and one of the most common causes of mortality among children under five years of age, when not appropriately managed. Infection of the lungs by bacteria, viruses, or fungi and consequent inflammation may lead to cough and difficult breathing. Some of the key predisposing factors are malnutrition and air pollution. WHO reports that Africa has the highest burden of global child mortality, and 16% of all deaths in pneumonia, were children under five years of age in 2016.

Objectives: This study aimed to explore how health providers perceive pneumonia as a cause of under-five mortality in Nigeria.

Methods: A qualitative study design with in-depth interviews and focus group discussions was used to explore and understand nurses and pediatricians' views regarding the pneumonia situation, vaccinations, and preventive suggestions to reduce under five pneumonia deaths in Nigeria.

Results: Two themes and four categories emerged: participant's anxiety over the situation, their views on impediments, current policies and strategies, and suggestions on addressing severe pneumonia.

Conclusions: The results from this study highlight contextual issues playing major roles in pneumonia mortality among children in Nigeria, which will need approaches on several levels to address them.

Place, publisher, year, edition, pages
MAKERERE UNIV, COLL HEALTH SCIENCES,SCH MED, 2023
Keywords
Pneumonia, children, under five mortality, Nigeria, vaccinations, barriers
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:uu:diva-510109 (URN)10.4314/ahs.v23i2.21 (DOI)001039372900021 ()
Available from: 2023-08-24 Created: 2023-08-24 Last updated: 2025-02-20Bibliographically approved
Aune, A., Vartdal, G., Bergseng, H., Randeberg, L. L. & Darj, E. (2020). Bilirubin estimates from smartphone images of newborn infants' skin correlated highly to serum bilirubin levels.. Acta Paediatrica, 109(12), 2532-2538
Open this publication in new window or tab >>Bilirubin estimates from smartphone images of newborn infants' skin correlated highly to serum bilirubin levels.
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2020 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 109, no 12, p. 2532-2538Article in journal (Refereed) Published
Abstract [en]

AIM: Neonatal jaundice is an important cause of morbidity and mortality, and identifying the condition remains a challenge. This study evaluated a novel method of estimating bilirubin levels from colour-calibrated smartphone images.

METHODS: A cross-sectional prospective study was undertaken at two hospitals in Norway from February 2017 to March 2019, with standardised illumination at one hospital and non-standardised illumination at the other hospital. Healthy term-born infants with a normal birthweight were recruited up to 15 days of age. The main outcome measures were bilirubin estimates from digital images, plus total bilirubin in serum (TSB) and transcutaneous bilirubin (TcB).

RESULTS: Bilirubin estimates were performed for 302 newborn infants, and 76 had severe jaundice. The correlation between the smartphone estimates and TSB was measured by Pearson's r and was .84 for the whole sample. The correlation between the image estimates and TcB was 0.81. There were no significant differences between the hospitals. Sensitivity was 100%, and specificity was 69% for identifying severe jaundice of more than 250 µmol/L.

CONCLUSION: A smartphone-based tool that estimated bilirubin levels from digital images identified severe jaundice with high sensitivity and could provide a screening tool for neonatal jaundice.

Keywords
digital images, hyperbilirubinaemia, mobile health, neonatal jaundice, smartphone
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:uu:diva-431237 (URN)10.1111/apa.15287 (DOI)000527297800001 ()32267569 (PubMedID)
Available from: 2021-01-13 Created: 2021-01-13 Last updated: 2025-02-20Bibliographically approved
Rishal, P., Devi Pun, K., Schei, B., Bhandari, B., Kumar Joshi, S., Swahnberg, K., . . . The Advance Study Group, . (2020). Improving Safety Among Pregnant Women Reporting Domestic Violence in Nepal-A Pilot Study.. International Journal of Environmental Research and Public Health, 17(7), Article ID E2268.
Open this publication in new window or tab >>Improving Safety Among Pregnant Women Reporting Domestic Violence in Nepal-A Pilot Study.
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2020 (English)In: International Journal of Environmental Research and Public Health, ISSN 1661-7827, E-ISSN 1660-4601, Vol. 17, no 7, article id E2268Article in journal (Refereed) Published
Abstract [en]

Introduction: Domestic violence (DV) during pregnancy is associated with poor health outcomes for both the mother and newborn, and sometimes death. In a low-income country like Nepal, women have few options to leave abusive situations. Therefore, there is a need for interventions to improve their safety. The aim of our study was to explore the use of safety measures before and after an educational intervention among women who have reported DV during pregnancy. Materials and methods: Of 1010 pregnant women screened consecutively for DV using the Abuse Assessment Screen (AAS) during routine antenatal care, 181 women reported domestic violence. All 1010 participating pregnant women were taught 15 safety measures using a locally developed flipchart. We obtained contact with 80 of the 181 eligible women postpartum, of whom 62 completed the follow-up assessment. We explored and described the use of safety measures at baseline and follow-up, using a standardized instrument called the Safety Behavior Checklist. Results: At follow-up, less than half of the women (n = 30, or 48.3%) reported any form of DV. Of the women who reported DV at follow-up, significantly more reported the experience of both violence and fear at baseline (21.9%, p = 0.01) compared with the women who did not report DV at follow-up (3.3%, p = 0.01). Women reporting DV at baseline and follow-up used more safety measures at baseline (56) and follow-up (80) compared with women reporting DV at baseline only (36 and 46). Women reporting DV at baseline and follow-up used more safety measures for the first time at follow-up, 57 new measures compared with the 28 new measures used by women reporting DV at baseline only. Conclusions: The use of a flipchart teaching session on safety measures within antenatal care may increase the number of safety measures women use to protect themselves during pregnancy and decrease the risks of adverse health effects of DV.

Place, publisher, year, edition, pages
MDPI AG, 2020
Keywords
Nepal, antenatal care, domestic violence, intervention, pregnancy, safety behaviors, safety measures
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:uu:diva-463751 (URN)10.3390/ijerph17072268 (DOI)000530763300100 ()32230945 (PubMedID)
Available from: 2022-01-11 Created: 2022-01-11 Last updated: 2025-02-20Bibliographically approved
Aune, A., Vartdal, G., Bergseng, H., Randeberg, L. L. & Darj, E. (2020). Response to letter to the editor [Letter to the editor]. Acta Paediatrica, 109(12), 2823-2823
Open this publication in new window or tab >>Response to letter to the editor
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2020 (English)In: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 109, no 12, p. 2823-2823Article in journal, Letter (Other academic) Published
Place, publisher, year, edition, pages
WILEY, 2020
National Category
Pediatrics
Identifiers
urn:nbn:se:uu:diva-439670 (URN)10.1111/apa.15400 (DOI)000544374600001 ()32506604 (PubMedID)
Available from: 2021-04-09 Created: 2021-04-09 Last updated: 2021-04-09Bibliographically approved
Pun, K. D., Tjomsland, T. R., Infanti, J. J. & Darj, E. (2020). 'Violence exists to show manhood': Nepali men's views on domestic violence - a qualitative study. Global Health Action, 13(1), Article ID 1788260.
Open this publication in new window or tab >>'Violence exists to show manhood': Nepali men's views on domestic violence - a qualitative study
2020 (English)In: Global Health Action, ISSN 1654-9716, E-ISSN 1654-9880, Vol. 13, no 1, article id 1788260Article in journal (Refereed) Published
Abstract [en]

Background

There is significant evidence of the prevalence and factors associated with domestic violence in high and low-income country settings. However, men’s views on domestic violence are still understudied and have never been reported in Nepali society.

Objective

The aim of the study was to explore Nepali men’s perceptions regarding domestic violence in their communities.

Method

The authors undertook a qualitative study using focus group discussions.

Results

Sixty-six married men, considered they were responsible for upholding family discipline and physically demonstrating their masculinity, and they suggested that violence was a mean for achieving this. Men’s frustration when unable to fulfil their family’s expectations or material needs, and cultural attitudes that precluded interference in other families’ lives, were perceived as factors contributing to domestic violence. The men held the opinion that women also perpetrated domestic violence. Some men were reluctant to accept domestic violence as a norm in Nepali families and were aware of recent changes in societal expectations regarding gender roles.

Conclusion

Overall, the Nepali men who participated in the study held different and sometimes opposing views on domestic violence, ranging from violence justified as a necessity for family discipline, uneasy acceptance that violence was commonplace in families, to definite opposition to the use of domestic violence. The study’s findings provide information for identifying points of intervention for violence-prevention efforts and strategies to alter the social and cultural norms that lead to acceptance of domestic violence.

Keywords
Domestic violence, masculinity, focus group discussions, men's perceptions, Nepal
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:uu:diva-419174 (URN)10.1080/16549716.2020.1788260 (DOI)000550529500001 ()32687002 (PubMedID)
Available from: 2020-09-14 Created: 2020-09-14 Last updated: 2025-02-20Bibliographically approved
Åhman, A., Edvardsson, K., Fagerli, T. A., Darj, E., Holmlund, S., Small, R. & Mogren, I. (2019). A much valued tool that also brings ethical dilemmas - a qualitative study of Norwegian midwives' experiences and views on the role of obstetric ultrasound. BMC Pregnancy and Childbirth, 19, Article ID 33.
Open this publication in new window or tab >>A much valued tool that also brings ethical dilemmas - a qualitative study of Norwegian midwives' experiences and views on the role of obstetric ultrasound
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2019 (English)In: BMC Pregnancy and Childbirth, ISSN 1471-2393, E-ISSN 1471-2393, Vol. 19, article id 33Article in journal (Refereed) Published
Abstract [en]

Background: Midwives are the main providers of routine antenatal care services including the routine ultrasound examination in Norway. The ultrasound examination can be perceived by expectant parents not only as a medical examination but also as a social event facilitating attachment to their fetus. This study explores Norwegian midwives' experiences and views on the role of ultrasound in clinical management of pregnancy.

Methods: A qualitative study design was applied. Twenty-four midwives who all performed obstetric ultrasound examinations were recruited for focus group discussions and individual interviews. Data collection took place in 2015 in five hospitals in two different regions of Norway. Data were analyzed using qualitative content analysis.

Results: Midwives described obstetric ultrasound examinations as very valuable although doing ultrasounds placed high demands on their operational and counselling skills. Increasing requests for ultrasound from pregnant women were mentioned. Advancements in ultrasound diagnosis were considered to have put the fetus in the position of a patient, and that pregnant women declining ultrasound could be viewed as irresponsible by some health professionals. Ethical concerns were raised regarding the possibility of pregnancy termination when fetal anomalies were detected. Fears were also expressed that prenatal diagnoses including those following ultrasound, might create a society where only perfect' children are valued. However, participants stressed that their intention in performing ultrasound was to optimize pregnancy outcome and thereby assist expectant couples and their unborn children.

Conclusions: Midwives in Norwegian maternity care services describe obstetric ultrasound as very valuable, playing a central role in pregnancy management by optimizing pregnancy outcomes. Although high demands are placed on operators' technical skills and counseling, midwives described performing obstetric ultrasound as very satisfying work. However, midwives believed that expectant parents' approach to the ultrasound examination, both its medical value and the precious images obtained of the fetus, could put extra strain on the midwives performing ultrasounds. The potential of ultrasound to detect fetal anomalies and the possibility that this may lead to termination of pregnancy, seemed to create some ambivalent feelings in midwives towards its use.

Place, publisher, year, edition, pages
BMC, 2019
Keywords
Pregnancy, Ultrasonography, Midwives, Qualitative research, Norway
National Category
Gynaecology, Obstetrics and Reproductive Medicine
Identifiers
urn:nbn:se:uu:diva-375866 (URN)10.1186/s12884-019-2178-x (DOI)000455891900001 ()30651083 (PubMedID)
Funder
Swedish Research Council, 2014-2672Forte, Swedish Research Council for Health, Working Life and WelfareVästerbotten County Council
Available from: 2019-02-04 Created: 2019-02-04 Last updated: 2025-02-11Bibliographically approved
Organisations
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0002-8311-4956

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