Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis CohortUniv Hosp North Norway, Dept Pediat, Tromso, Norway.;UiT Arctic Univ Norway, Fac Hlth Sci, Dept Clin Med, Tromso, Norway..
UiT Arctic Univ Norway, Fac Hlth Sci, Dept Clin Med, Tromso, Norway.;Univ Hosp North Norway, Dept Otorhinolaryngol, Tromso, Norway.;Univ Hosp North Norway, Div Oral & Maxillofacial Surg, Tromso, Norway.;Publ Dent Serv Competence Ctr North Norway, Tromso, Norway..
NTNU, Fac Med & Hlth Sci, Dept Clin & Mol Med, Trondheim, Norway.;Nord Trondelag Hosp Trust, Levanger Hosp, Dept Pediat, Levanger, Norway..
NTNU, Fac Med & Hlth Sci, Dept Clin & Mol Med, Trondheim, Norway.;St Olavs Hosp, Dept Pediat, Trondheim, Norway..
St Olavs Hosp, Dept Oral & Craniomaxillofacial Surg, Trondheim, Norway..
Univ Gothenburg, Sahlgrenska Acad, Dept Pediat, Gothenburg, Sweden..
Inst Postgrad Dent Educ, Dept Oral & Maxillofacial Surg Stomatognath Physi, Jönköping, Sweden..
Univ Helsinki, Hosp Children & Adolescents, Helsinki, Finland..
Univ Helsinki, Hosp Children & Adolescents, Helsinki, Finland..
Univ Helsinki, Orthodont Oral & Maxillofacial Dis, Helsinki, Finland.;Helsinki Univ Hosp, Helsinki, Finland..
Copenhagen Univ Hosp, Dept Pediat, Copenhagen, Denmark..
Copenhagen Univ Hosp, Dept Pediat, Copenhagen, Denmark..
Univ Copenhagen, Dept Pediat Dent & Clin Genet, Copenhagen, Denmark..
Aarhus Univ Hosp, Dept Pediat, Palle Juul Jensens Blvd 99, DK-8200 Aarhus N, Denmark..
Aarhus Univ, Sect Orthodont, Aarhus, Denmark.;Aarhus Univ Hosp, Dept Oral & Maxillofacial Surg, Aarhus, Denmark..
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2020 (English)In: Journal of Rheumatology, ISSN 0315-162X, E-ISSN 1499-2752, Vol. 47, no 5, p. 730-738Article in journal (Refereed) Published
Abstract [en]
Objective: To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset.
Methods: Drawn from a prospective, population-based Nordic JIA cohort with disease onset from 1997 to 2000, 420 consecutive cases were eligible for orofacial evaluation of TMJ involvement. The followup visit included demographic data, a standardized clinical orofacial examination, and full-face cone-beam computed tomography (CBCT). For comparison, 200 age-matched healthy controls were used.
Results: Of 420 eligible participants with JIA, 265 (63%) were included (mean age 23.5 +/- 4.2 yrs) and completed a standardized clinical orofacial examination. Of these, 245 had a full-face CBCT performed. At least 1 orofacial symptom was reported by 33%. Compared to controls, the JIA group significantly more often reported TMJ pain, TMJ morning stiffness, and limitation on chewing. Further, among participants reporting complaints, the number of symptoms was also higher in JIA. The mean maximal incisal opening was lower in the JIA group (p < 0.001), and TMJ pain on palpation was more frequent. Condylar deformities and/or erosions were observed in 61% as assessed by CBCT, showing bilateral changes in about 70%. Risk factors of condylar deformities were orofacial dysfunction or biologic treatment; enthesitis-related arthritis was protective.
Conclusion: This study of the longterm consequences of TMJ involvement in a population-based JIA cohort reports persistence of comprehensive symptoms, dysfunctions, and damage of the TMJ into adulthood. We suggest interdisciplinary followup of JIA patients also in adulthood.
Place, publisher, year, edition, pages
J RHEUMATOL PUBL CO , 2020. Vol. 47, no 5, p. 730-738
Keywords [en]
TEMPOROMANDIBULAR JOINT, JUVENILE IDIOPATHIC ARTHRITIS, OUTCOMES
National Category
Rheumatology and Autoimmunity Dentistry
Identifiers
URN: urn:nbn:se:uu:diva-424634DOI: 10.3899/jrheum.190231ISI: 000578891700015PubMedID: 31523047OAI: oai:DiVA.org:uu-424634DiVA, id: diva2:1499442
2020-11-092020-11-092024-10-17Bibliographically approved
In thesis