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Objective: The study aimed to investigate acceptability of a clinical trial, the Fex-Can Sex intervention, a web-based program targeting sexual dysfunction following cancer.

Methods: Young adults (aged 19–40) who reported sexual dysfunction 1.5 years after a cancer diagnosis were drawn from a population-based cohort and invited to a two-armed randomized controlled trial. Participants in the intervention group (n=572) participated in a 12-week web-based psychoeducational self-help program. The program was guided by self-determination theory, and developed in collaboration with former patients with cancer. Apart from testing the efficacy of the intervention, study-specific items were used to assess experiences of the program’s different parts. Additionally, the intervention group answered open-ended questions about their thoughts of the program and/or sexuality which were analyzed with thematic analysis.

Results: The post-intervention items were completed by 56 participants (78%). The majority appreciated the program (73%) and would recommend it to others (91%), and 18% reported that their sexual problems had improved. Analysis of the participants’ experiences resulted in four main themes: Perceived benefits, Barriers to participation, Not for me, and Suggestions for the future.

Conclusion and implications: Participants’ experiences of the program were generally positive, supporting acceptability. Revision of the program to Fex-Can 2.0 is currently ongoing.