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Computationally efficient dilated residual networks for segmentation of major cerebral vessels in MRA
Department of Electrical Engineering, National Institute of Technology, Durgapur, West Bengal, India.
Department of Radio Diagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Radiology. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Neuroradiology.ORCID iD: 0000-0002-5221-2721
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Radiology. Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Neuroradiology.ORCID iD: 0000-0002-9481-6857
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2025 (English)In: Network Modeling Analysis in Health Informatics and Bioinformatics, ISSN 2192-6670, Vol. 14, no 1, article id 95Article in journal (Refereed) Published
Abstract [en]

Subarachnoid hemorrhages, often caused by ruptured cerebral aneurysms, require precise vessel segmentation for early intervention and surgical planning. Volumetric segmentation of cerebral vasculature is essential for stroke screening and treatment response assessment. However, the small size and complex topology of cerebral vessels pose significant challenges for clinically reliable segmentation. In this paper, we propose a novel dilated residual-based network for segmenting the major cerebral vessels. The major cerebral vessels provide high contextual information of location of aneurysms. Anatomical information of the location of cerebral aneurysm remnants is used for better segmentation and lightweight network development. An extensive quantitative and visual assessment has been done with state-of-the-art networks for cerebral vessel segmentation. Our proposed method demonstrated promising result with dice score of 0.94 on in-house Aneurysm Database. Furthermore, with the help of neuro-interventional radiologists, we have analyzed the relevance of major cerebral vessels segmentation for aneurysm quantification in streamlining endovascular surgical planning as the method attains higher level of accuracy and maintains consistency in preserving vascular pathology. A novel, robust, cerebral vessel segmentation method was proposed. The method provides the relevance of vessel segmentation, paving the way for improved diagnostic accuracy and clinical decision-making in intracranial aneurysms.

Place, publisher, year, edition, pages
Springer Nature, 2025. Vol. 14, no 1, article id 95
Keywords [en]
Anatomy-guided segmentation, Magnetic resonance angiography (MRA), Major cerebral vasculature, Quantification of aneurysm, Surgical planning
National Category
Medical Imaging Radiology and Medical Imaging Neurology
Identifiers
URN: urn:nbn:se:uu:diva-567694DOI: 10.1007/s13721-025-00551-zISI: 001562542900001Scopus ID: 2-s2.0-105015055130OAI: oai:DiVA.org:uu-567694DiVA, id: diva2:2001466
Funder
VinnovaEU, Horizon 2020Available from: 2025-09-26 Created: 2025-09-26 Last updated: 2025-09-26Bibliographically approved

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Toumpanakis, DimitriosWikström, JohanStrand, Robin

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