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Samverkan kring äldre personer med multisjuklighet: En studie av hur nationella reformer och nya arbetssätt påverkar återinläggning på sjukhus inom 30 dagar
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Public Health and Caring Sciences, Health Services Research.ORCID iD: 0000-0002-3036-1048
2025 (Swedish)Doctoral thesis, comprehensive summary (Other academic)
Description
Abstract [en]

Heart failure poses a significant challenge in healthcare, contributing substantially to morbidity and mortality. The overall aim of the thesis was to investigate how collaboration between different health and social care providers affects hospital readmissions within 30 days among older adults with multimorbidity, with a particular focus on those with heart failure. It investigates the impacts of local and national reforms, and post-discharge care options. Study I explored the effect of heart failure nurses in a Swedish primary care setting on readmission outcomes. Contrary to expectations, the presence of heart failure nurses did not significantly reduce readmission rates. It seems that it might be the role assigned to specific heart failure nurses, rather than simply having this resource that could improve outcomes. Study II evaluated effects of the Swedish Care Coordination Act on persons >65 years with multimorbidity and heart failure. The study found no significant impact on readmission or mortality rates following the implementation of the Care Coordination Act. This suggests that the Care Coordination Act 's structured mandates alone may be insufficient to cater to older persons with more complex care needs, such as those with heart failure. Study III investigated the effect of discharge to a nursing home for older patients with multimorbidity. Discharges to nursing homes resulted in a marked reduction in short-term readmissions and mortality compared to home-based care. The study highlights the central role of monitoring when it comes to older persons with multimorbidity following a hospital admission which may explain why nursing homes offer short time benefits. In the longer term decision-making requires consideration of patient preferences and clinical assessments. Study IV examined healthcare leaders' perspectives on the 30-day readmission indicator. Leaders recognized its widespread use but emphasized the need for more integrated system-level analysis and patient-centered care to achieve meaningful reductions in readmission. They advocated for top-level leadership to set clear goals and ensure system-wide accountability.

Taken together, this thesis identified no positive effects of the local or national interventions, highlighting the difficulty of developing effective policy and interventions to improve post-discharge outcomes for heart failure patients.  Future success may depend on better implementation of coordinated individual plans and concerted efforts across the healthcare system. Patients with the most complex care needs may for instance benefit from dedicated care coordinators responsible for managing and integrating their care.

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2025. , p. 84
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 2208
Keywords [en]
Health policy, Heart failure, Heart failure nurse, Nursing homes, End-of-life, Health care costs, Propensity score matching, Hospitalization, Long-term care
National Category
Medical and Health Sciences
Research subject
Medical Science
Identifiers
URN: urn:nbn:se:uu:diva-570457ISBN: 978-91-513-2655-9 (print)OAI: oai:DiVA.org:uu-570457DiVA, id: diva2:2009392
Public defence
2025-12-16, Sal X, Universitetshuset, Biskopsgatan 3, Uppsala, 09:00 (Swedish)
Opponent
Supervisors
Available from: 2025-11-25 Created: 2025-10-27 Last updated: 2025-11-25
List of papers
1. Introduction of specialized heart failure nurses in primary care and its impact on readmissions
Open this publication in new window or tab >>Introduction of specialized heart failure nurses in primary care and its impact on readmissions
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2022 (English)In: Primary Health Care Research and Development, ISSN 1463-4236, E-ISSN 1477-1128, Vol. 23, article id e78Article in journal (Refereed) Published
Abstract [en]

Background: Heart failure (HF) has a 2% prevalence in the population and is a major cause of morbidity and mortality. Multiple efforts have been made worldwide to improve quality of care and decrease unplanned readmissions for HF patients, one of which has been the introduction of specialist HF nurses (HFN) in primary health care. The present evidence on the benefits of HFN is contradicting. This study aims to evaluate the impact of a quality improvement intervention, availability of a HFN in Swedish primary care, on hospital readmissions.

Methods: All patients over the age of 65 with a HF diagnosis and with complete information on availability of a HFN were included in this retrospective register-based study. Using propensity score matching (PSM) techniques, two comparable groups of 128 patients each were created according to the exposure status, availability or no availability of a HFN. The rate of readmission was compared between the groups.

Results: Using PSM, 256 patients were matched, 128 in the HFN group and 128 in the no-HFN group. A total of 50% and 46.09% of patients in the HFN and no-HFN groups were readmitted, respectively. Mean number of readmissions per patient was 1.19 (SD 0.61) in the HFN group and 1.10 (SD 0.44) in the no-HFN group. Patients in the HFN had 17.6% higher odds of being readmitted during the study period, OR: 1.176 (CI: 0.716-1.932), and 3.8% lower odds of being readmitted within 30 days, OR: 0.962 (CI: 0.528-1.750).

Conclusions: Availability of a HFN in primary care was not significantly associated with reduced readmissions for the patients included in this study. Further investigations are warranted looking at the impacts of availability and access to a HFN in primary care on readmissions and other patient outcomes.

Place, publisher, year, edition, pages
Cambridges Institutes Press, 2022
Keywords
care programmes, heart failure, heart failure nurse, quality improvement, readmission
National Category
Public Health, Global Health and Social Medicine
Identifiers
urn:nbn:se:uu:diva-491735 (URN)10.1017/S1463423622000676 (DOI)000894604500001 ()36484241 (PubMedID)
Available from: 2023-01-03 Created: 2023-01-03 Last updated: 2025-10-27Bibliographically approved
2. The impact of the Swedish Care Coordination Act on heart failure readmissions and length of stay
Open this publication in new window or tab >>The impact of the Swedish Care Coordination Act on heart failure readmissions and length of stay
2025 (English)In: Circulation Heart Failure, ISSN 1941-3289, E-ISSN 1941-3297, Vol. 18, no 12, article id e012567Article in journal (Refereed) Published
Abstract [en]

Background

Heart failure patients tend to experience higher rates of hospital readmissions compared to other ambulatory care-sensitive conditions. In Sweden, the nationwide Care Coordination Act (CCA) was introduced in January 2018 with the goal of improving care coordination resulting in a reduction of readmissions and length of stay. There is insufficient knowledge regarding the effect of this reform on heart failure patients.

Methods

We studied the association of implementing CCA on all cause 30-day readmissions and length of stay for patients over 65 years of age with ICD-50 heart failure. The dataset included all admissions with a primary diagnosis of heart failure among elderly, multimorbid patients between 2015 and 2019. An interrupted time series analysis using hierarchical mixed models with random effects clustered at the hospital ward level was conducted.

Results

A total of 111 414 admissions were included. The average readmission rate for heart failure patients was 26.8 % before and 26.7 % after the CCA. The average length of stay (LOS) was 8.4 days before the CCA and 8.1 days after. Mortality within 30 days was 7.3 % before the CCA and 7.5 % after. There were no significant differences between the periods before and after. In an analysis assessing the overall linear time trend 2 of 21 regions showed a reduction in readmissions and 10 in length of stay.

Conclusions

After the introducing the CCA, no detectable impact was found on readmissions or mortality for heart failure patients, which is in line with previous studies such as those studying the US Hospital Readmission Reduction Program. While no overall association on length of stay could be identified, it was reduced in a number of the Swedish regions. The heterogeneity between regions could be used to understand the specific components needed to achieve reduction of readmissions in future studies.

Place, publisher, year, edition, pages
American Heart Association, 2025
National Category
Public Health, Global Health and Social Medicine Health Care Service and Management, Health Policy and Services and Health Economy Cardiology and Cardiovascular Disease
Research subject
Medical Science
Identifiers
urn:nbn:se:uu:diva-570455 (URN)10.1161/CIRCHEARTFAILURE.124.012567 (DOI)001639376300010 ()41170562 (PubMedID)
Available from: 2025-10-24 Created: 2025-10-24 Last updated: 2026-01-12Bibliographically approved
3. The causal impact of discharge to nursing home on readmission and mortality: A propensity score matched analysis
Open this publication in new window or tab >>The causal impact of discharge to nursing home on readmission and mortality: A propensity score matched analysis
(English)Manuscript (preprint) (Other academic)
Abstract [en]

Background

The hospital discharge process entails substantial challenges, particularly among older multimorbid patients with a high risk of subsequent readmission and/or death. Discharging hospitals often face a decision regarding whether such patients should be discharged to a short- or long-term stay at a nursing home, or sent home with community-based support services. Our aim is to investigate whether and how these forms of post-inpatient care impact readmission and mortality rates.

Methods

We used data from nationally comprehensive Swedish health- and social care registries during 2015 to 2019 to perform a retrospective analysis using a target trial emulation design. The study included multimorbid patients over 65, who lived at home prior to hospitalization, and were subsequently discharged to either a nursing home or to their own residence with formal home care interventions. To estimate the average treatment effect of nursing home vs in-home care, each patient discharged to a nursing home was matched to a patient discharged home using a propensity score generated by a machine-learning model based on the patients previous medical and social care history. Outcomes were assessed using survival analysis.

Results

Patients discharged to nursing homes had a substantially lower risk of hospital readmission across 7-, 30- and 90-day endpoints, with Hazard Ratios of 0.53, 0.69, and 0.83 respectively. Short term (7 day) mortality was lower for nursing home patients (HR 0.59), but was by 30 days similar (HR 1.02), and higher by 90 days (HR 1.37).

Discussion

Our findings suggest substantial short-term benefits of nursing home care in terms of reduced readmission and mortality rates. The causal effect of nursing home care on longer term outcomes is more uncertain, and may be influenced by residual confounding not captured by the propensity score. In practice, factors such as availability of care placements, patient preferences, and the clinical team's assessment influence discharge decisions. Based on our findings, an additional advantage of nursing home placement may be considered: A reduced risk of readmission and short-term mortality, benefiting both patients and the healthcare system.

National Category
Health Care Service and Management, Health Policy and Services and Health Economy
Research subject
Medical Science
Identifiers
urn:nbn:se:uu:diva-570449 (URN)
Available from: 2025-10-24 Created: 2025-10-24 Last updated: 2025-10-27
4. Reducing 30-Day Readmissions in Elderly Heart Failure Patients: An interview study with Swedish Healthcare Leaders
Open this publication in new window or tab >>Reducing 30-Day Readmissions in Elderly Heart Failure Patients: An interview study with Swedish Healthcare Leaders
(English)Manuscript (preprint) (Other academic)
Abstract [en]

Introduction

30-day readmission is an indicator of integrated care between health care providers including primary care. While some studies have demonstrated effective models for improvement, most countries, including Sweden, have not shown significant progress. This study aims to understand what health care leaders suggest can be done to reduce readmissions, as well as how they value the indicator itself.

Method

Semi-structured interviews of fifteen primary care and internal medicine leaders in general practice and internal medicine, qualitatively analyzed by a framework model.

Results

Four main themes, with altogether nine subthemes were identified. The leaders pointed out that readmissions is a widely used indicator. They identify multiple areas for reducing readmissions like involving the patients more and improve system-level thinking.

Discussion

30-day readmission is analyzed, but seldom together with other providers. Key for improving readmissions is to create a safe and secure atmosphere for patients and relatives and to develop a better system thinking, the latter which is outside the interviewed leaders’ own jurisdiction. 

Conclusion

The leaders have a clear view of what is needed to reduce readmissions, however the top leadership has to set specific goals and follow up on all levels in the system. 

National Category
Health Care Service and Management, Health Policy and Services and Health Economy
Research subject
Medical Science
Identifiers
urn:nbn:se:uu:diva-570451 (URN)
Available from: 2025-10-24 Created: 2025-10-24 Last updated: 2025-10-27

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Sarkadi Kristiansson, Robert

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