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Nutrition impact symptoms 6-12 months post-burn injury: a single-cohort longitudinal study
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Plastic Surgery. Burn Centre, Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden. (Plastikkirurgi)ORCID iD: 0000-0003-2806-5159
Uppsala University, Disciplinary Domain of Humanities and Social Sciences, Faculty of Social Sciences, Department of Food Studies, Nutrition and Dietetics.ORCID iD: 0000-0001-9795-0624
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Plastic Surgery. Burn Centre, Department of Plastic and Maxillofacial Surgery, Uppsala University Hospital, Uppsala, Sweden. (Plastikkirurgi)ORCID iD: 0000-0002-9735-1434
Section Clinical Nutrition, Karolinska University Hospital, Stockholm, Sweden; Gastroenterology and nutrition unit, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
(English)Manuscript (preprint) (Other academic)
Abstract [en]

Objectives 

This study aimed to investigate long-term prevalence of nutrition impact symptoms, such as appetite and eating-related issues that may impede food intake, in patients with minor- and major-burn injuries.

Methods

In this prospective longitudinal cohort study, sixty adults participated. Two questionnaires, the Disease-Related Appetite Questionnaire (DRAQ-burn) and the Eating Symptom Questionnaire (ESQ-burn), were completed during follow-up visits at six and 12 months post trauma.

Results

Median burn extent was 4.5% in the post-minor burn group and 24.0% in the post-major burn group. At six months, the median number of symptoms reported in DRAQ-burn was 2.0 for all patients; at 12 months, it was 1.0 post-minor burns and 1.5 post-major burns. Reported symptoms in the ESQ-burn remained stable at a median of 1.0 across both time points and burn severities. Most frequently reported symptoms included fluctuation in appetite/eating, never/rarely feeling hungry, tiredness affecting appetite/eating and nausea. No statistically significant differences were found between burn severity groups or over time.

Conclusion

Overall, although the nutrition impact symptoms were reported to be more mild than severe in nature, they persisted for up to a year post burn, highlighting the need for ongoing nutritional follow-up to mitigate the risk of malnutrition.

Keywords [en]
Burn injury, Nutrition impact symptoms
National Category
Anesthesiology and Intensive Care Rehabilitation Medicine Nutrition and Dietetics
Research subject
Medical Science
Identifiers
URN: urn:nbn:se:uu:diva-576047OAI: oai:DiVA.org:uu-576047DiVA, id: diva2:2028260
Available from: 2026-01-14 Created: 2026-01-14 Last updated: 2026-01-21
In thesis
1. Nutritional therapy post-burn injury: Adherence to guidelines and an analysis of nutritional interventions and barriers
Open this publication in new window or tab >>Nutritional therapy post-burn injury: Adherence to guidelines and an analysis of nutritional interventions and barriers
2026 (English)Doctoral thesis, comprehensive summary (Other academic)
Abstract [en]

Objective: Insufficient nutritional intake can impair wound healing and increase the risk of complications post burn. The overall aim of this thesis was to examine nutritional therapy post burn in relation to the extent of the burn. This was accomplished by examining adherence to nutritional guidelines (Study I), documented interventions and barriers (Study II), and symptoms affecting appetite and eating post injury (Study III-IV).

Methods: Study I evaluated documented nutritional therapy in relation to guidelines during first 12 days post burn by conducting medical record review. Study II explored differences in documentation of nutritional interventions and barriers between patients post-minor and major burn by performing medical record review and content analysis. Study III modified questionnaires Disease Related Appetite Questionnaire (DRAQ) and Eating Symptom Questionnaire (ESQ) to measure nutrition impact symptoms (NIS) 6-12 months post burn by undertaken expert panel review, cognitive interviews and expert consultation on terminology. Study IV investigated the differences in prevalence of NIS using questionnaires DRAQ-burn and ESQ-burn.

Results: Study I found low adherence to nutritional guidelines and low adequacy of intake compared to individual goals, particularly after minor burns. Study II showed that interventions targeting meal and meal support were rarely documented compared to medical nutritional therapy, despite most patients having oral intake. Barriers to nutritional therapy were common with fasting and gastrointestinal symptoms being the most frequently documented. Significantly more interventions and barriers were documented for patients post-major burn compared to post-minor burn. In Study III high expert consensus on the adapted questionnaires DRAQ-burn and ESQ-burn was achieved. Study IV revealed prevalences of median 1-2 NIS at 6 months that persisted up to 12 months post injury. There was no difference in the prevalence of NIS post-minor compared to post-major burn.

Conclusions: The overall low adherence to nutritional guidelines, inadequate achievement of individual intake goals, the frequent documentation of barriers to nutritional interventions, and the persistent prevalence of nutrition impact symptoms indicate a risk of insufficient nutritional therapy following burn. The findings highlight the need for continuous nutritional assessment, evaluation and monitoring of nutritional therapy throughout the burn care trajectory regardless of burn extent. 

Place, publisher, year, edition, pages
Uppsala: Acta Universitatis Upsaliensis, 2026. p. 82
Series
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 1651-6206 ; 2226
Keywords
Burn, Nutrition, Nutritional therapy, Intervention, Barrier, Nutrition impact symptom, guideline
National Category
Clinical Medicine
Research subject
Medical Science
Identifiers
urn:nbn:se:uu:diva-576103 (URN)978-91-513-2717-4 (ISBN)
Public defence
2026-03-06, H:son Holmdahlsalen, Uppsala University hospital, entrance 100, 2nd floor, Dag Hammarskjölds väg 8, Uppsala, 09:15 (English)
Opponent
Supervisors
Available from: 2026-02-13 Created: 2026-01-14 Last updated: 2026-02-13

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Dimander, JosefinAndersson, AgnetaHuss, Fredrik

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