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Nociceptive, neuropathic, or nociplastic low back pain?: The low back pain phenotyping (BACPAP) consortium's international and multidisciplinary consensus recommendations
Vrije Univ Brussel, Fac Phys Educ & Physiotherapy, Dept Physiotherapy Human Physiol & Anat, Pain Mot Res Grp, Brussels, Belgium.;Univ Hosp Brussels, Dept Phys Med & Physiotherapy, Chron Pain Rehabil, Brussels, Belgium.;Univ Gothenburg, Inst Neurosci & Physiol, Unit Physiotherapy, Dept Hlth & Rehabil,Sahlgrenska Acad, Gothenburg, Sweden.;Vrije Univ Brussel, Fac Phys Educ & Physiotherapy, Dept Physiotherapy Human Physiol & Anat, Pain Mot Res Grp, B-1090 Brussels, Belgium..ORCID iD: 0000-0002-4976-6563
Uppsala University, Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Surgical Sciences, Pain. Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden..ORCID iD: 0000-0003-0488-8177
Univ Med Ctr Rotterdam, Erasmus MC, Dept Gen Practice, Rotterdam, Netherlands.;Duke Univ, Dept Hlth Sci, Durham, NC USA..ORCID iD: 0000-0003-2350-9945
Duke Univ, Dept Orthopaed Surg, Durham, NC USA.;Duke Univ, Duke Clin Res Inst, Durham, NC USA.;Duke Univ, Dept Populat Hlth Sci, Durham, NC USA..
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2024 (English)In: The Lancet Rheumatology, E-ISSN 2665-9913, Vol. 6, no 3, p. e178-e188Article in journal (Refereed) Published
Abstract [en]

The potential to classify low back pain as being characterised by dominant nociceptive, neuropathic, or nociplastic mechanisms is a clinically relevant issue. Preliminary evidence suggests that these low back pain phenotypes might respond differently to treatments; however, more research must be done before making specific recommendations. Accordingly, the low back pain phenotyping (BACPAP) consortium was established as a group of 36 clinicians and researchers from 13 countries (five continents) and 29 institutions, to apply a modified Nominal Group Technique methodology to develop international and multidisciplinary consensus recommendations to provide guidance for identifying the dominant pain phenotype in patients with low back pain, and potentially adapt pain management strategies. The BACPAP consortium's recommendations are also intended to provide direction for future clinical research by building on the established clinical criteria for neuropathic and nociplastic pain. The BACPAP consortium's consensus recommendations are a necessary early step in the process to determine if personalised pain medicine based on pain phenotypes is feasible for low back pain management. Therefore, these recommendations are not ready to be implemented in clinical practice until additional evidence is generated that is specific to these low back pain phenotypes.

Place, publisher, year, edition, pages
Elsevier, 2024. Vol. 6, no 3, p. e178-e188
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Neurosciences Neurology
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URN: urn:nbn:se:uu:diva-527053DOI: 10.1016/S2665-9913(23)00324-7ISI: 001196847100001PubMedID: 38310923OAI: oai:DiVA.org:uu-527053DiVA, id: diva2:1854678
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Available from: 2024-04-26 Created: 2024-04-26 Last updated: 2024-06-24Bibliographically approved

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Nijs, JoKosek, EvaChiarotto, AlessandroKoes, BartOstelo, RaymondScholten-Peeters, Gwendolyne G. M.Bilika, ParaskeviHuysmans, EvaMalfliet, AnneleenSmeets, Rob
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